Protein Kinase, AMP-Activated, Alpha 2 Catalytic Subunit (PRKAA2) Antibody from ABBEXA LTD
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| Antigenic Specificity | Protein Kinase, AMP-Activated, Alpha 2 Catalytic Subunit (PRKAA2) |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2a kappa |
| Format | Protein G purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB, IF/ICC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. |
| Immunogen | Human PRKAA2 recombinant protein. |
| Other Names | 5' AMP activated protein kinase catalytic alpha 1 chain, 5' AMP activated protein kinase catalytic alpha 2 chain, 5' AMP activated protein kinase catalytic subunit alpha 1, 5' AMP activated protein kinase catalytic subunit alpha 2, 5''-AMP-activated protein kinase catalytic subunit alpha-1, ACACA kinase, Acetyl-CoA carboxylase kinase, AMP activate kinase alpha 1 subunit, AMP activated protein kinase alpha 2 catalytic subunit, AMP activated protein kinase catalytic alpha 1, AMPK 1, AMPK 2, AMPK alpha 1 chain, AMPK alpha 2 chain, AMPK, AMPK subunit alpha-1, AMPK1, AMPK2, AMPKa1, HMGCR kinase, Hydroxymethylglutaryl-CoA reductase kinase, MGC33776, MGC57364, PRKAA 1, PRKAA 2, PRKAA, PRKAA1, PRKAA2, Protein kinase AMP activated alpha 1 catalytic subunit, Protein kinase AMP activated alpha 2 catalytic subunit, Tau-protein kinase PRKAA1, 5'-AMP-activated protein kinase catalytic subunit alpha-2, AMPK subunit alpha-2, AMPKa2, Alpha2 AMPK, AMPK alpha 2, AMPK-2, AMPKalpha2, Ampk alpha2, AMPK-alph |
| Gene, Accession # | UniProt: P54646 |
| Catalog # | abx025251 |
| Price | please inquire |
| Order / More Info | Protein Kinase, AMP-Activated, Alpha 2 Catalytic Subunit (PRKAA2) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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