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Antigenic Specificity | Protein Tyrosine Phosphatase, Non Receptor Type 11 (PTPN11) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG1 kappa |
Format | Protein G purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. |
Immunogen | Human PTPN11 recombinant protein. |
Other Names | BPTP3, CFC, MGC14433, NS1, PTP-1D, PTP2C, SH-PTP2, SH-PTP3, SHP2, SH-PTP, PTPN11, SHPTP2, Tyrosine-protein phosphatase non-receptor type 11, Protein-tyrosine phosphatase 1D, Protein-tyrosine phosphatase 2C, protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1), SHP-2, Noonan syndrome 1, protein tyrosine phosphatase, non-receptor type 11, PTP-2C, BPTP3, BPTP3, BPTP3 , BPTP3 , CFC, CFC, CFC , CFC , MGC14433, MGC14433, MGC14433 , MGC14433 , NS1, NS1, NS1 , NS1 , PTP-1D, PTP-1D, PTP-1D , PTP-1D , PTP2C, PTP2C, PTP2C , PTP2C , SH-PTP2, SH-PTP2, SH-PTP2 , SH-PTP2 , SH-PTP3, SH-PTP3, SH-PTP3 , SH-PTP3 , SHP2, SHP2, SHP2 , SHP2 , SH-PTP, SH-PTP, SH-PTP , SH-PTP , PTPN11, PTPN11, PTPN11 , PTPN11 , SHPTP2, SHPTP2, SHPTP2 , SHPTP2 , Tyrosine-protein phosphatase non-receptor type 11, Tyrosine-protein phosphatase non-receptor type 11, Tyrosine-protein phosphatase non-receptor type 11 , Tyrosine-protein phosphatase non-receptor type 11 , Protein-tyrosine phosphatase 1D, |
Gene, Accession # | UniProt: Q06124 |
Catalog # | abx025290 |
Price | please inquire |
Order / More Info | Protein Tyrosine Phosphatase, Non Receptor Type 11 (PTPN11) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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