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Antigenic Specificity | MAP4K4 (pS629) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, DB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | M4K4, a member of the STE20 subfamily of Ser/Thr protein kinases, may play a role in the response to environmental stress and cytokines such as TNF-alpha. It appears to act upstream of the JUN N-terminal pathway. This protein is thought to interact with the SH3 domain of the adapter proteins Nck. HGK binds, via its CNH regulatory domain, to the N-terminal region of SPG3A. Expression appears to be ubiquitous, expressed in all tissue types examined. Isoform 5 appears to be more abundant in the brain, and isoform 4 is predominant in the liver, skeletal muscle and placenta. |
Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S629 of human MAP4K4. |
Other Names | HGK, NIK, MEKKK4, FLH21957, MAP4K4, FLJ10410, FLJ20373, FLJ90111, KIAA0687, HPK/GCK-like kinase HGK, M4K4, MAPK/ERK kinase kinase kinase 4, MEK kinase kinase 4, MEKKK 4, Nck interacting kinase, hepatocyte progenitor kinase-like/germinal center kinase-like kinase, mitogen-activated protein kinase kinase kinase kinase 4, HGK, HGK , HGK , HGK, NIK, NIK , NIK , NIK, MEKKK4, MEKKK4 , MEKKK4 , MEKKK4, FLH21957, FLH21957 , FLH21957 , FLH21957, MAP4K4, MAP4K4 , MAP4K4 , MAP4K4, FLJ10410, FLJ10410 , FLJ10410 , FLJ10410, FLJ20373, FLJ20373 , FLJ20373 , FLJ20373, FLJ90111, FLJ90111 , FLJ90111 , FLJ90111, KIAA0687, KIAA0687 , KIAA0687 , KIAA0687, HPK/GCK-like kinase HGK, HPK/GCK-like kinase HGK , HPK/GCK-like kinase HGK , HPK/GCK-like kinase HGK, M4K4, M4K4 , M4K4 , M4K4, MAPK/ERK kinase kinase kinase 4, MAPK/ERK kinase kinase kinase 4 , MAPK/ERK kinase kinase kinase 4 , MAPK/ERK kinase kinase kinase 4, MEK kinase kinase 4, MEK kinase kinase 4 , MEK kinase kinase 4 , MEK kinase kinase |
Gene, Accession # | UniProt: O95819 |
Catalog # | abx031979 |
Price | please inquire |
Order / More Info | MAP4K4 (pS629) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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