Mouse Smarcd1 Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-Mouse Smarcd1 antibody, protein, ELISA kits.
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| Antigenic Specificity | Mouse Smarcd1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Smarcd1 is involved in chromatin remodeling. Has a strong influence on the Vitamin D-mediated transcriptional activity from an enhancer Vitamin D receptor element (VDRE). May be a link between mammalian SWI-SNF-like chromatin remodeling complexes and the vitamin D receptor (VDR) heterodimer. Mediates critical interactions between nuclear receptors and the BRG1/SMARCA4 chromatin-remodeling complex for transactivation. Also involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene (By similarity). Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth. |
| Immunogen | KLH-conjugated synthetic peptide between 309-335 amino acids from the Central region of mouse Smarcd1. |
| Other Names | Smarcd1, Baf60a, D15Kz1, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1, 60 kDa BRG-1/Brm-associated factor subunit A, BRG1-associated factor 60A, Protein D15KZ1, SWI/SNF complex 60 kDa subunit, Smarcd1, Smarcd1, Smarcd1 , Smarcd1 , Baf60a, Baf60a, Baf60a , Baf60a , D15Kz1, D15Kz1, D15Kz1 , D15Kz1 , SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 , SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 , 60 kDa BRG-1/Brm-associated factor subunit A, 60 kDa BRG-1/Brm-associated factor subunit A, 60 kDa BRG-1/Brm-associated factor subunit A , 60 kDa BRG-1/Brm-associated factor subunit A , BRG1-associated factor 60A, BRG1-associated factor 60A, BRG1-associated factor |
| Gene, Accession # | UniProt: Q61466 |
| Catalog # | abx031126 |
| Price | please inquire |
| Order / More Info | Mouse Smarcd1 Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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