Autophagy Related Protein 7 (ATG7) Antibody from ABBEXA LTD
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| Antigenic Specificity | Autophagy Related Protein 7 (ATG7) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG7 functions as an E1 enzyme essential for multisubstrates such as GABARAPL1 and ATG12. APG3L is an E2-like conjugating enzyme facilitating covalent binding of APG8 (MAP1LC3) to phosphatidylethanolamine (PE). APG7 (an E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with APG3. Formation of the PE conjugate is essential for autophagy. |
| Immunogen | KLH-conjugated synthetic peptide between 284-313 amino acids from the Central region of human ATG7. |
| Other Names | ATG7, Ubiquitin-activating enzyme E1-like protein, ATG7 autophagy related 7 homolog (S. cerevisiae), APG7-LIKE, APG7L, DKFZp434N0735, GSA7, HAGP7, Autophagy Related 7, Autophagy-Related Protein 7, APG7 Autophagy 7-Like (S. Cerevisiae), Ubiquitin-like modifier-activating enzyme ATG7, ATG12-activating enzyme E1 ATG7, ATG7, ATG7, ATG7 , ATG7 , Ubiquitin-activating enzyme E1-like protein, Ubiquitin-activating enzyme E1-like protein, Ubiquitin-activating enzyme E1-like protein , Ubiquitin-activating enzyme E1-like protein , ATG7 autophagy related 7 homolog (S. cerevisiae), ATG7 autophagy related 7 homolog (S. cerevisiae), ATG7 autophagy related 7 homolog (S. cerevisiae) , ATG7 autophagy related 7 homolog (S. cerevisiae) , APG7-LIKE, APG7-LIKE, APG7-LIKE , APG7-LIKE , APG7L, APG7L, APG7L , APG7L , DKFZp434N0735, DKFZp434N0735, DKFZp434N0735 , DKFZp434N0735 , GSA7, GSA7, GSA7 , GSA7 , HAGP7, HAGP7, HAGP7 , HAGP7 , Autophagy Related 7, Autophagy Related 7, Autophagy Related 7 , Autoph |
| Gene, Accession # | NCBI: NP_001129503.2, NP_001138384.1, NP_006386.1, UniProt: O95352 |
| Catalog # | abx030053 |
| Price | please inquire |
| Order / More Info | Autophagy Related Protein 7 (ATG7) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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