Cyclin Dependent Kinase Inhibitor 1A (CDKN1A) Antibody from ABBEXA LTD

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Antigenic SpecificityCyclin Dependent Kinase Inhibitor 1A (CDKN1A)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size20 µl, 50 µl, 100 µl, 200 µl
Concentration> 0.5 mg/ml
ApplicationsWB, IF/ICC
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DescriptionCDKN1A antibody is a Rabbit polyclonal antibody against CDKN1A. This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-CDK2 or -CDK4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen (PCNA), a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of CDK2, and may be instrumental in the execution of apoptosis following caspase activation. Multiple alternatively spliced variants have been found for this gene.
ImmunogenRecombinant protein of human CDKN1A.
Other NamesCAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1, CDKN1A, MDA6, PIC1, Cyclin-dependent kinase inhibitor 1, CDK-interacting protein 1, Melanoma differentiation-associated protein 6, CAP20, CAP20, CAP20 , CAP20 , CDKN1, CDKN1, CDKN1 , CDKN1 , CIP1, CIP1, CIP1 , CIP1 , MDA-6, MDA-6, MDA-6 , MDA-6 , P21, P21, P21 , P21 , SDI1, SDI1, SDI1 , SDI1 , WAF1, WAF1, WAF1 , WAF1 , p21CIP1, p21CIP1, p21CIP1 , p21CIP1 , CDKN1A, CDKN1A, CDKN1A , CDKN1A , MDA6, MDA6, MDA6 , MDA6 , PIC1, PIC1, PIC1 , PIC1 , Cyclin-dependent kinase inhibitor 1, Cyclin-dependent kinase inhibitor 1, Cyclin-dependent kinase inhibitor 1 , Cyclin-dependent kinase inhibitor 1 , CDK-interacting protein 1, CDK-interacting protein 1, CDK-interacting protein 1 , CDK-interacting protein 1 , Melanoma differentiation-associated protein 6, Melanoma differentiation-associated protein 6, Melanoma differentiation-associated protein 6 , Melanoma differentiation-associated protein 6
Gene, Accession #CDKN1A, Gene ID: 1026, UniProt: P38936
Catalog #abx001260
Priceplease inquire
Order / More InfoCyclin Dependent Kinase Inhibitor 1A (CDKN1A) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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