ZAP70 (pY493) Antibody from ABBEXA LTD
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| Antigenic Specificity | ZAP70 (pY493) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 50 µl, 100 µl, 200 µl, |
| Concentration | > 0.5 mg/ml |
| Applications | WB, IHC, IF/ICC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | ZAP70 (pY493) antibody is a Rabbit polyclonal antibody against ZAP70 (pY493). This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. |
| Immunogen | Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding Y493 of human ZAP70. |
| Other Names | ZAP70, zeta-chain (TCR) associated protein kinase 70kDa, FLJ17670, FLJ17679, SRK, STD, TZK, ZAP-70, 70 kDa zeta-associated protein, syk-related tyrosine kinase, tyrosine-protein kinase ZAP-70, zeta-chain associated protein kinase, 70kD, ZA70, kinase ZAP70, ZAP70, ZAP70, ZAP70 , ZAP70 , zeta-chain (TCR) associated protein kinase 70kDa, zeta-chain (TCR) associated protein kinase 70kDa, zeta-chain (TCR) associated protein kinase 70kDa , zeta-chain (TCR) associated protein kinase 70kDa , FLJ17670, FLJ17670, FLJ17670 , FLJ17670 , FLJ17679, FLJ17679, FLJ17679 , FLJ17679 , SRK, SRK, SRK , SRK , STD, STD, STD , STD , TZK, TZK, TZK , TZK , ZAP-70, ZAP-70, ZAP-70 , ZAP-70 , 70 kDa zeta-associated protein, 70 kDa zeta-associated protein, 70 kDa zeta-associated protein , 70 kDa zeta-associated protein , syk-related tyrosine kinase, syk-related tyrosine kinase, syk-related tyrosine kinase , syk-related tyrosine kinase , tyrosine-protein kinase ZAP-70, tyrosine-protein kinase ZAP-70, tyro |
| Gene, Accession # | ZAP70, Gene ID: 7535, UniProt: P43403 |
| Catalog # | abx000515 |
| Price | please inquire |
| Order / More Info | ZAP70 (pY493) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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