Metalloproteinase Inhibitor 3 (TIMP3) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-Metalloproteinase Inhibitor 3 (TIMP3) antibody, protein, ELISA kits.
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| Antigenic Specificity | Metalloproteinase Inhibitor 3 (TIMP3) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 20 µl, 50 µl, 100 µl, 200 µl |
| Concentration | > 0.5 mg/ml |
| Applications | WB, IF/ICC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | TIMP3 Antibody is a Rabbit Polyclonal antibody against TIMP3. TIMPs are members of the family of tissue inhibitor of matrix metalloproteinases (MMPs) that includes TIMP1, TIMP2, TIMP3, and TIMP4. The main function of TIMPs is their inhibitory effect on MMPs. TIMPs irreversibly inactivate MMPs by direct binding to their catalytic zinc cofactor and resultant inhibition of proteinase function. In addition to MMP inhibition, TIMPs have also been shown to interact with various membrane receptors on the cell surface. Some of these interactions include: TIMP1 with CD63, TIMP2 with α3β1 integrin, and TIMP3 with VEGFR2, all of which result in distinct cellular effects. TIMPs are involved in a wide variety of biological functions, such as tumor angiogenesis and progression, wound healing, and vascular remodeling (6,7). Mutations in TIMP3 are associated with Sorsby?s fundus dystrophy. |
| Immunogen | Recombinant protein of human TIMP3. |
| Other Names | HSMRK222, K222, K222TA2, Metalloproteinase inhibitor 3, MIG-5 protein, Protein MIG-5, SFD, TIMP metallopeptidase inhibitor 3, TIMP-3, TIMP3, Tissue inhibitor of metalloproteinases 3, HSMRK222, HSMRK222, HSMRK222, HSMRK222, K222, K222, K222, K222, K222TA2, K222TA2, K222TA2, K222TA2, Metalloproteinase inhibitor 3, Metalloproteinase inhibitor 3, Metalloproteinase inhibitor 3, Metalloproteinase inhibitor 3, MIG-5 protein, MIG-5 protein, MIG-5 protein, MIG-5 protein, Protein MIG-5, Protein MIG-5, Protein MIG-5, Protein MIG-5, SFD, SFD, SFD, SFD, TIMP metallopeptidase inhibitor 3, TIMP metallopeptidase inhibitor 3, TIMP metallopeptidase inhibitor 3, TIMP metallopeptidase inhibitor 3, TIMP-3, TIMP-3, TIMP-3, TIMP-3, TIMP3, TIMP3, TIMP3, TIMP3, Tissue inhibitor of metalloproteinases 3, Tissue inhibitor of metalloproteinases 3, Tissue inhibitor of metalloproteinases 3, Tissue inhibitor of metalloproteinases 3 |
| Gene, Accession # | TIMP3, Gene ID: 7078, UniProt: P35625 |
| Catalog # | abx001273 |
| Price | please inquire |
| Order / More Info | Metalloproteinase Inhibitor 3 (TIMP3) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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