PDZ Domain Containing 3 (PDZD3) Antibody from ABBEXA LTD
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| Antigenic Specificity | PDZ Domain Containing 3 (PDZD3) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Guanylyl cyclase C (GCC, or GUCY2C; MIM 601330) produces cGMP following the binding of either endogenous ligands or heat-stable enterotoxins secreted by E. coli and other enteric bacteria. Activation of GCC initiates a signaling cascade that leads to phosphorylation of the cystic fibrosis transmembrane conductance regulator (CFTR; MIM 602421), followed by a net efflux of ions and water into the intestinal lumen. IKEPP is a regulatory protein that associates with GCC and regulates the amount of cGMP produced following receptor stimulation (Scott et al., 2002 [PubMed 11950846]). |
| Immunogen | KLH-conjugated synthetic peptide between 258-285 amino acids from the Central region of human PDZD3. |
| Other Names | Na(+)/H(+) exchange regulatory cofactor NHE-RF4, NHERF-4, Intestinal and kidney-enriched PDZ protein, Natrium-phosphate cotransporter IIa C-terminal-associated protein 2, Na/Pi cotransporter C-terminal-associated protein 2, NaPi-Cap2, PDZ domain-containing protein 2, PDZ domain-containing protein 3, Sodium-hydrogen exchanger regulatory factor 4, PDZD3, IKEPP, NHERF4, PDZK2, DLNB27, Na (+) /H (+) exchange regulatory cofactor NHE-RF4, Na(+)/H(+) exchange regulatory cofactor NHE-RF4, Na(+)/H(+) exchange regulatory cofactor NHE-RF4, Na(+)/H(+) exchange regulatory cofactor NHE-RF4 , Na(+)/H(+) exchange regulatory cofactor NHE-RF4 , NHERF-4, NHERF-4, NHERF-4 , NHERF-4 , Intestinal and kidney-enriched PDZ protein, Intestinal and kidney-enriched PDZ protein, Intestinal and kidney-enriched PDZ protein , Intestinal and kidney-enriched PDZ protein , Natrium-phosphate cotransporter IIa C-terminal-associated protein 2, Natrium-phosphate cotransporter IIa C-terminal-associated protein 2, Natrium |
| Gene, Accession # | PDZD3, UniProt: Q86UT5 |
| Catalog # | abx029676 |
| Price | please inquire |
| Order / More Info | PDZ Domain Containing 3 (PDZD3) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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