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Antigenic Specificity | Histone H2A.X (H2AFX) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein G purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation. |
Immunogen | KLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human H2AFX. |
Other Names | H2A.X, H2A/X, H2AX, Histone H2A.X, H2AFX, H2A.X, H2A.X, H2A.X , H2A.X , H2A/X, H2A/X, H2A/X , H2A/X , H2AX, H2AX, H2AX , H2AX , Histone H2A.X, Histone H2A.X, Histone H2A.X , Histone H2A.X , H2AFX, H2AFX, H2AFX , H2AFX |
Gene, Accession # | NCBI: NP_002096.1, UniProt: P16104 |
Catalog # | abx034840 |
Price | please inquire |
Order / More Info | Histone H2A.X (H2AFX) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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