Histone Acetyltransferase Tip60 (TIP60) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-Histone Acetyltransferase Tip60 (TIP60) antibody, protein, ELISA kits.
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| Antigenic Specificity | Histone Acetyltransferase Tip60 (TIP60) |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2b |
| Format | ascites |
| Size | 100 µl, |
| Concentration | n/a |
| Applications | ELISA, WB, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | HTATIP (HIV-1 Tat interacting protein TIP60, about 60kDa) belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4), is the primary building block of chromatin. In addition to the growing number of post-translational histone modifications regulating chromatin structure, cells can also exchange canonical histones with variant histones that can directly or indirectly modulate chromatin structure. There are five major variants of histone H2A: canonical H2A (most abundant), H2A.X, MacroH2A, H2ABbd and H2A.Z. Histone H2A.Z, the most conserved variant across species, functions as both a positive and negative regulator of transcription and is important for chromosome stability. Several homologous protein complexes, such as SWR-C, TIP60 and SRCAP (mammals), have been shown to catalyze the ATP-dependent exchange of H2A.Z for H2A in the nucleosome. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. |
| Immunogen | Purified recombinant fragment of human TIP60 expressed in E. Coli. |
| Other Names | 60 kDa Tat interactive protein, cPLA (2)-interacting protein, histone acetyltransferase HTATIP, HIV-1 Tat interactive protein, HTATIP, Tat-interactive 60 kDa protein alpha isoform, Tat-interactive protein-60, TI60, 60 kDa Tat-interactive protein, cPLA2, cPLA2 interacting protein, ESA1, Histone acetyltransferase KAT5, 60kDa, HTATIP1, K (lysine) acetyltransferase 5, K-acetyltransferase 5, KAT5, Lysine acetyltransferase 5, PLIP, Tat interacting protein, TIP, TIP60, 60 kDa Tat interactive protein, 60 kDa Tat interactive protein, 60 kDa Tat interactive protein , 60 kDa Tat interactive protein , cPLA (2)-interacting protein, cPLA (2)-interacting protein, cPLA (2)-interacting protein , cPLA (2)-interacting protein , histone acetyltransferase HTATIP, histone acetyltransferase HTATIP, histone acetyltransferase HTATIP , histone acetyltransferase HTATIP , HIV-1 Tat interactive protein, HIV-1 Tat interactive protein, HIV-1 Tat interactive protein , HIV-1 Tat interactive protein , HTATIP, HTAT |
| Gene, Accession # | KAT5, Gene ID: 10524, UniProt: Q92993 |
| Catalog # | abx010956 |
| Price | please inquire |
| Order / More Info | Histone Acetyltransferase Tip60 (TIP60) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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