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Antigenic Specificity | PKC beta 2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat, monkey |
Isotype | n/a |
Format | Protein G purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Protein kinase C (PKC) is a family of serine and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. PKC beta is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported. Isoform 1 uses an alternate exon at the 3' end compared to isoform 2, which includes a part of the coding region. The resulting isoform 1 has a distinct and shorter C-terminus, as compared to isoform 2. |
Immunogen | KLH-conjugated synthetic peptide between 642-673 amino acids from the C-terminal region of human PKC beta2. |
Other Names | PRKCB, PKCB, PRKCB1, Protein kinase C beta type, PRKCB, PRKCB , PRKCB , PRKCB, PKCB, PKCB , PKCB , PKCB, PRKCB1, PRKCB1 , PRKCB1 , PRKCB1, Protein kinase C beta type, Protein kinase C beta type , Protein kinase C beta type , Protein kinase C beta type |
Gene, Accession # | UniProt: P05771-2 |
Catalog # | abx025114 |
Price | please inquire |
Order / More Info | PKC beta 2 Antibody from ABBEXA LTD |
Product Specific References | n/a |
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