Recombination Activating Gene 2 (RAG2) Antibody from ABBEXA LTD

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Antigenic SpecificityRecombination Activating Gene 2 (RAG2)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpeptide affinity purified
Size80 µl, 400 µl,
Concentrationn/a
ApplicationsELISA, WB, IHC, FCM
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionThis product is currently in development. The lead time for this product may be several months. Please contact us at info@abbexa.com for an updated lead time before purchasing this product.

This gene encodes a protein that is involved in the initiation of V (D) J recombination during B and T cell development. This protein forms a complex with the product of the adjacent recombination activating gene 1, and this complex can form double-strand breaks by cleaving DNA at conserved recombination signal sequences. The recombination activating gene 1 component is thought to contain most of the catalytic activity, while the N-terminal of the recombination activating gene 2 component is thought to form a six-bladed propeller in the active core that serves as a binding scaffold for the tight association of the complex with DNA. A C-terminal plant homeodomain finger-like motif in this protein is necessary for interactions with chromatin components, specifically with histone H3 that is trimethylated at lysine 4. Mutations in this gene cause Omenn syndrome, a form of severe combined immunodeficiency associated with autoimmune-like symptoms.
ImmunogenKLH-conjugated synthetic peptide between 349-377 amino acids from the C-terminal region of human RAG2.
Other NamesRAG-2, RAG2, V (D) J recombination-activating protein 2, RAG-2, RAG-2, RAG-2 , RAG-2 , RAG2, RAG2, RAG2 , RAG2 , V (D) J recombination-activating protein 2, V (D) J recombination-activating protein 2, V (D) J recombination-activating protein 2 , V (D) J recombination-activating protein 2
Gene, Accession #UniProt: P55895
Catalog #abx026817
Priceplease inquire
Order / More InfoRecombination Activating Gene 2 (RAG2) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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