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Antigenic Specificity | Serine/Threonine-Protein Kinase DCLK2 (DCLK2) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. Mouse studies show that the DCX gene, another family member, and this gene share function in the establishment of hippocampal organization and that their absence results in a severe epileptic phenotype and lethality, as described in human patients with lissencephaly. Multiple alternatively spliced transcript variants have been identified. |
Immunogen | KLH-conjugated synthetic peptide between 167-196 amino acids from the N-terminal region of human DCLK2. |
Other Names | DCLK2, Doublecortin Like Kinase 2, DCDC3B, DCK2, DCAMKL2, DCDC3, Doublecortin Domain-Containing Protein 3B, Doublecortin-Like And CAM Kinase-Like 2, Serine/Threonine-Protein Kinase DCLK2, Doublecortin And CaM Kinase-Like 2, CaMK-Like CREB Regulatory Kinase 2, Doublecortin-Like Kinase 2, EC 2.7.11.1, MGC45428, CLICK-II, CLICK2, CL2, EC 2.7.11, CLIK2, DCLK2, DCLK2, DCLK2 , DCLK2 , Doublecortin Like Kinase 2, Doublecortin Like Kinase 2, Doublecortin Like Kinase 2 , Doublecortin Like Kinase 2 , DCDC3B, DCDC3B, DCDC3B , DCDC3B , DCK2, DCK2, DCK2 , DCK2 , DCAMKL2, DCAMKL2, DCAMKL2 , DCAMKL2 , DCDC3, DCDC3, DCDC3 , DCDC3 , Doublecortin Domain-Containing Protein 3B, Doublecortin Domain-Containing Protein 3B, Doublecortin Domain-Containing Protein 3B , Doublecortin Domain-Containing Protein 3B , Doublecortin-Like And CAM Kinase-Like 2, Doublecortin-Like And CAM Kinase-Like 2, Doublecortin-Like And CAM Kinase-Like 2 , Doublecortin-Like And CAM Kinase-Like 2 , Serine/Threonine-Protein Kin |
Gene, Accession # | DCLK2, Gene ID: 166614, UniProt: Q8N568 |
Catalog # | abx031317 |
Price | please inquire |
Order / More Info | Serine/Threonine-Protein Kinase DCLK2 (DCLK2) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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