Tumor Necrosis Factor Ligand Superfamily Member 11 / RANKL (TNFSF11) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-Tumor Necrosis Factor Ligand Superfamily Member 11 / RANKL (TNFSF11) antibody, protein, ELISA kits.
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| Antigenic Specificity | Tumor Necrosis Factor Ligand Superfamily Member 11 / RANKL (TNFSF11) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 20 µl, 50 µl, 100 µl, 200 µl |
| Concentration | > 0.5 mg/ml |
| Applications | WB, IHC, IF/ICC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | TNFSF11 Antibody is a Rabbit Polyclonal antibody against TNFSF11. This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss. This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in the regulation of cell apoptosis. Targeted disruption of the related gene in mice led to severe osteopetrosis and a lack of osteoclasts. The deficient mice exhibited defects in early differentiation of T and B lymphocytes, and failed to form lobulo-alveolar mammary structures during pregnancy. Two alternatively spliced transcript variants have been found. |
| Immunogen | Recombinant protein of human TNFSF11. |
| Other Names | CD254, hRANKL2, ODF, OPGL, OPTB2, Osteoclast differentiation factor, Osteoprotegerin ligand, RANKL, receptor activator of nuclear factor kappa B ligand, Receptor activator of nuclear factor kappa-B ligand, sOdf, TNF-related activation-induced cytokine, TNF11, TNFSF11, TRANCE, tumor necrosis factor ligand superfamily, member 11, Tumor necrosis factor ligand superfamily member 11, Receptor activator of nuclear factor kappa-B liga, CD254 antigen, Tumor nec, membrane form, soluble form, CD254, CD254, CD254, CD254, hRANKL2, hRANKL2, hRANKL2, hRANKL2, ODF, ODF, ODF, ODF, OPGL, OPGL, OPGL, OPGL, OPTB2, OPTB2, OPTB2, OPTB2, Osteoclast differentiation factor, Osteoclast differentiation factor, Osteoclast differentiation factor, Osteoclast differentiation factor, Osteoprotegerin ligand, Osteoprotegerin ligand, Osteoprotegerin ligand, Osteoprotegerin ligand, RANKL, RANKL, RANKL, RANKL, receptor activator of nuclear factor kappa B ligand, receptor activator of nuclear factor kappa B ligand, receptor activator of nuclear factor kappa B ligand, receptor activator of nuclear factor kappa B ligand, Receptor activator of nuclear factor kappa-B ligand, Receptor activator of nuclear factor kappa-B ligand, Receptor activator of nuclear factor kappa-B ligand, Receptor activator of nuclear factor kappa-B ligand, sOdf, sOdf, sOdf, sOdf, TNF-related activation-induced cytokine, TNF-related activation-induced cytokine, TNF-related activation-induced cytokine, TNF-related activation-induced cytokine, TNF11, TNF11, TNF11, TNF11, TNFSF11, TNFSF11, TNFSF11, TNFSF11, TRANCE, TRANCE, TRANCE, TRANCE, tumor necrosis factor ligand superfamily, tumor necrosis factor ligand superfamily, tumor necrosis factor ligand superfamily, tumor necrosis factor ligand superfamily, member 11, member 11, member 11, member 11, Tumor necrosis factor ligand superfamily member 11, Tumor necrosis factor ligand superfamily member 11, Tumor necrosis factor ligand superfamily member 11, Tumor necrosis factor ligand superfamily member 11, Receptor activator of nuclear factor kappa-B liga, Receptor activator of nuclear factor kappa-B liga, Receptor activator of nuclear factor kappa-B liga, Receptor activator of nuclear factor kappa-B liga, CD254 antigen, CD254 antigen, CD254 antigen, CD254 antigen, Tumor nec, Tumor nec, Tumor nec, Tumor nec, membrane form, membrane form, membrane form, membrane form, soluble form, soluble form, soluble form, soluble form |
| Gene, Accession # | TNFSF11, Gene ID: 8600, UniProt: O14788 |
| Catalog # | abx001988 |
| Price | please inquire |
| Order / More Info | Tumor Necrosis Factor Ligand Superfamily Member 11 / RANKL (TNFSF11) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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