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Antigenic Specificity | Interferon Regulatory Factor 9 (IRF9) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC, IF/ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | IRF9 is a transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state. |
Immunogen | KLH-conjugated synthetic peptide between 75-104 amino acids from the N-terminal region of human IRF9. |
Other Names | IRF9, Interferon regulatory factor 9, ISGF3 p48 subunit, ISGF3G, p48, IRF-9, ISGF3, ISGF-3 gamma, IFN-alpha-responsive transcription factor subunit, Interferon-stimulated gene factor 3 gamma, Transcriptional regulator ISGF3 subunit gamma, RF-9, IRF9, IRF9, IRF9 , IRF9 , Interferon regulatory factor 9, Interferon regulatory factor 9, Interferon regulatory factor 9 , Interferon regulatory factor 9 , ISGF3 p48 subunit, ISGF3 p48 subunit, ISGF3 p48 subunit , ISGF3 p48 subunit , ISGF3G, ISGF3G, ISGF3G , ISGF3G , p48, p48, p48 , p48 , IRF-9, IRF-9, IRF-9 , IRF-9 , ISGF3, ISGF3, ISGF3 , ISGF3 , ISGF-3 gamma, ISGF-3 gamma, ISGF-3 gamma , ISGF-3 gamma , IFN-alpha-responsive transcription factor subunit, IFN-alpha-responsive transcription factor subunit, IFN-alpha-responsive transcription factor subunit , IFN-alpha-responsive transcription factor subunit , Interferon-stimulated gene factor 3 gamma, Interferon-stimulated gene factor 3 gamma, Interferon-stimulated gene factor 3 gamma , I |
Gene, Accession # | UniProt: Q00978 |
Catalog # | abx026485 |
Price | please inquire |
Order / More Info | Interferon Regulatory Factor 9 (IRF9) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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