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Antigenic Specificity | 26S Proteasome Regulatory Subunit 6B (PSMC4) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | > 0.5 mg/ml |
Applications | WB, IF/ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | 26S Proteasome Regulatory Subunit 6B (PSMC4) Antibody is a Rabbit Polyclonal antibody against 26S Proteasome Regulatory Subunit 6B (PSMC4). The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the triple-A family of ATPases that is a component of the 19S regulatory subunit and plays a role in 26S proteasome assembly. The encoded protein interacts with gankyrin, a liver oncoprotein, and may also play a role in Parkinson?s disease through interactions with synphilin-1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
Immunogen | Recombinant protein of human PSMC4. |
Other Names | 26S protease regulatory subunit 6B, 26S proteasome AAA-ATPase subunit RPT3, MB67-interacting protein, MIP224, Proteasome 26S subunit ATPase 4, Tat-binding protein 7, TBP-7, PSMC4, TBP7, proteasome (prosome, macropain) 26S subunit, ATPase, 4, MGC13687, MGC23214, MGC8570, S6, RPT3, 26S protease regulatory subunit 6B, 26S protease regulatory subunit 6B, 26S protease regulatory subunit 6B, 26S protease regulatory subunit 6B, 26S proteasome AAA-ATPase subunit RPT3, 26S proteasome AAA-ATPase subunit RPT3, 26S proteasome AAA-ATPase subunit RPT3, 26S proteasome AAA-ATPase subunit RPT3, MB67-interacting protein, MB67-interacting protein, MB67-interacting protein, MB67-interacting protein, MIP224, MIP224, MIP224, MIP224, Proteasome 26S subunit ATPase 4, Proteasome 26S subunit ATPase 4, Proteasome 26S subunit ATPase 4, Proteasome 26S subunit ATPase 4, Tat-binding protein 7, Tat-binding protein 7, Tat-binding protein 7, Tat-binding protein 7, TBP-7, TBP-7, TBP-7, TBP-7, PSMC4, PSMC4, PSMC4, PSMC4, TBP7, TBP7, TBP7, TBP7, proteasome (prosome, proteasome (prosome, proteasome (prosome, proteasome (prosome, macropain) 26S subunit, macropain) 26S subunit, macropain) 26S subunit, macropain) 26S subunit, ATPase, ATPase, ATPase, ATPase, 4, 4, 4, 4, MGC13687, MGC13687, MGC13687, MGC13687, MGC23214, MGC23214, MGC23214, MGC23214, MGC8570, MGC8570, MGC8570, MGC8570, S6, S6, S6, S6, RPT3, RPT3, RPT3, RPT3 |
Gene, Accession # | PSMC4, Gene ID: 5704, NCBI Accession: NP_006494.1, NM_006503.3, NP_694546.1, NM_153001.2, UniProt: P43686 |
Catalog # | abx001948 |
Price | please inquire |
Order / More Info | 26S Proteasome Regulatory Subunit 6B (PSMC4) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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