Fibroblast Growth Factor Receptor 4 (FGFR4) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-Fibroblast Growth Factor Receptor 4 (FGFR4) antibody, protein, ELISA kits.
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| Antigenic Specificity | Fibroblast Growth Factor Receptor 4 (FGFR4) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | Protein G purified |
| Size | 50 µl, 200 µl, |
| Concentration | n/a |
| Applications | ELISA, WB, IHC, FCM |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | FGFR4 is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. The genomic organization of the gene, compared to members 1-3, encompasses 18 exons rather than 19 or 20. Although alternative splicing has been observed, there is no evidence that the C-terminal half of the IgIII domain of this protein varies between three alternate forms, as indicated for members 1-3. This particular family member preferentially binds acidic fibroblast growth factor and, although its specific function is unknown, it is overexpressed in gynecological tumor samples, suggesting a role in breast and ovarian tumorigenesis. |
| Immunogen | KLH-conjugated synthetic peptide between 24-55 amino acids from the N-terminal region of human FGFR4. |
| Other Names | FGFR-4, CD334 antigen, FGFR4, JTK2, TKF, Fibroblast growth factor receptor 4, CD334, FGFR-4, FGFR-4, FGFR-4 , FGFR-4 , CD334 antigen, CD334 antigen, CD334 antigen , CD334 antigen , FGFR4, FGFR4, FGFR4 , FGFR4 , JTK2, JTK2, JTK2 , JTK2 , TKF, TKF, TKF , TKF , Fibroblast growth factor receptor 4, Fibroblast growth factor receptor 4, Fibroblast growth factor receptor 4 , Fibroblast growth factor receptor 4 , CD334, CD334, CD334 , CD334 |
| Gene, Accession # | NCBI: NP_002002.3, NP_075252.2, NP_998812.1, UniProt: P22455 |
| Catalog # | abx033563 |
| Price | please inquire |
| Order / More Info | Fibroblast Growth Factor Receptor 4 (FGFR4) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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