Sirtuin 6 (SIRT6) Antibody from ABBEXA LTD
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| Antigenic Specificity | Sirtuin 6 (SIRT6) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | NAD-dependent protein deacetylase. Has deacetylase activity towards 'Lys-9' and 'Lys-56' of histone H3. Modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Deacetylates 'Lys-9' of histone H3 at NF-kappa-B target promoters and may down-regulate the expression of a subset of NF-kappa-B target genes. Deacetylation of nucleosomes interferes with RELA binding to target DNA. May be required for the association of WRN with telomeres during S-phase and for normal telomere maintenance. Required for genomic stability. Required for normal IGF1 serum levels and normal glucose homeostasis. Modulates cellular senescence and apoptosis. Regulates the production of TNF protein (By similarity). |
| Immunogen | KLH-conjugated synthetic peptide between 276-305 amino acids from the C-terminal region of human SIRT6. |
| Other Names | Regulatory protein SIR2 homolog 6, SIR2-like protein 6, SIRT6, SIR2L6, NAD-dependent protein deacetylase sirtuin-6, sirtuin (silent mating type information regulation 2 homolog) 6 (S. cerevisiae), Regulatory protein SIR2 homolog 6, Regulatory protein SIR2 homolog 6, Regulatory protein SIR2 homolog 6 , Regulatory protein SIR2 homolog 6 , SIR2-like protein 6, SIR2-like protein 6, SIR2-like protein 6 , SIR2-like protein 6 , SIRT6, SIRT6, SIRT6 , SIRT6 , SIR2L6, SIR2L6, SIR2L6 , SIR2L6 , NAD-dependent protein deacetylase sirtuin-6, NAD-dependent protein deacetylase sirtuin-6, NAD-dependent protein deacetylase sirtuin-6 , NAD-dependent protein deacetylase sirtuin-6 , sirtuin (silent mating type information regulation 2 homolog) 6 (S. cerevisiae), sirtuin (silent mating type information regulation 2 homolog) 6 (S. cerevisiae), sirtuin (silent mating type information regulation 2 homolog) 6 (S. cerevisiae) , sirtuin (silent mating type information regulation 2 homolog) 6 (S. cerevisiae) |
| Gene, Accession # | SIRT6, UniProt: Q8N6T7 |
| Catalog # | abx027742 |
| Price | please inquire |
| Order / More Info | Sirtuin 6 (SIRT6) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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