IL6 (Siltuximab biosimilar) Antibody from ABBEXA LTD

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Antigenic SpecificityIL6 (Siltuximab biosimilar)
Clonemonoclonal
Host SpeciesChimeric Human/Mouse
Reactive Specieshuman
IsotypeIgG1 kappa
FormatProtein A/G purified
Size100 µg, 1 mg,
Concentrationtypically between 0.5-2.0 mg/ml.
ApplicationsELISA, WB
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DescriptionSiltuximab is a monoclonal antibody biosimilar expressed in CHO cells, targeting IL6, for use in laboratory research applications. This product is not suitable for use as medicines or in human, therapeutic or diagnostic applications.

Siltuximab is a chimeric (human-mouse) monoclonal immunoglobulin G1-kappa antibody produced in a Chinese hamster ovary (CHO) cell line by recombinant DNA technology. Siltuximab prevents the binding of IL-6 to soluble and membrane-bound IL-6 receptors by forming high affinity complexes with human interleukin-6 (IL-6). Its use is indicated for the treatment of adult patients with multicentric Castleman's disease (MCD) who are human immunodeficiency virus (HIV) negative and human herpesvirus-8 (HHV-8) negative. MCD is a rare blood disorder caused by dysregulated IL-6 production, proliferation of lymphocytes, and subsequent enlargement of the lymph nodes. It is administered as a 1 hour intravenous infusion every 3 weeks.
Immunogenn/a
Other NamesSiltuximab, IL6, 541502-14-1
Gene, Accession #CAS: 541502-14-1
Catalog #abx831169
Priceplease inquire
Order / More InfoIL6 (Siltuximab biosimilar) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
181 Cambridge Science Park
Cambridge, CB4 0GJ UK
P: +44 (0) 1223 755950

Customer Service: info@abbexa.com
Technical Support: support@abbexa.com
Orders: orders@abbexa.com

https://www.abbexa.com

U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413

Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950


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