Cyclic ADP Ribose Hydrolase (CD38) Antibody from ABBEXA LTD

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Antigenic SpecificityCyclic ADP Ribose Hydrolase (CD38)
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatascites
Size100 µl,
Concentrationn/a
ApplicationsELISA, WB, IHC
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DescriptionCD38 is a type II integral membrane glycoprotein which is present on early B and T cell lineages and activated B and T cells but is absent from most mature resting peripheral lymphocytes. CD38 is also found on thymocytes, pre-B cells, germinal center B cells, mitogen-activated T cells, monocytes and Ig-secreting plasma cells. CD38 acts as a NAD glycohydrolase in T lym- phocytes. On hematopoietic cells CD38 induces activation, proliferation, and differentiation of mature T and B cells and mediates apoptosis of myeloid and lymphoid progenitor cells. In addition to acting as a signaling receptor, CD38 is also an enzyme capable of producing several calcium-mobilizing metabo- lites, including cyclic adenosine diphosphate ribose (cADPR). CD38 also plays a role in maintaining survival of an invariant NK T (iNKT) cell subset that preferentially contributes to the maintenance of immunological tolerance.
ImmunogenPurified recombinant fragment of human CD38 expressed in E. Coli.
Other NamesCD38, Cyclic ADP Ribose Hydrolase, Cyclic ADP Ribose Hydrolase 1, CD38 Molecule, ADP-Ribosyl Cyclase 1, 2-Phospho-Cyclic-ADP-Ribose Transferase, Cyclic ADP-Ribose Hydrolase 1, 2-Phospho-ADP-Ribosyl Cyclase, NAD(+) Nucleosidase, CD38 Antigen (P45), ADPRC, ADPRC 1, 2-Phospho-ADP-Ribosyl Cyclase/2-Phospho-Cyclic-ADP-Ribose Transferase, 2-Phospho-ADP-Ribosyl Cyclase, 2-Phospho-Cyclic-ADP-Ribose Transferase, Ecto-Nicotinamide Adenine Dinucleotide Glycohydrolase, ADP-Ribosyl Cyclase/Cyclic ADP-Ribose Hydrolase 1, ADP-Ribosyl Cyclase, Cyclic ADP-Ribose Hydrolase 1, Cluster Of Differentiation 38, CADPr Hydrolase 1, CD38 Antigen, EC 2.4.99.20, EC 3.2.2.6, ADPRC1, T10, cADPRH, cADPRH 1, cADPRH1, 2'-phospho-ADP-ribosyl cyclase, 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase, 2'-phospho-cyclic-ADP-ribose transferase, cADPr hydrolase 1, CD38, CD38, CD38 , CD38 , Cyclic ADP Ribose Hydrolase, Cyclic ADP Ribose Hydrolase, Cyclic ADP Ribose Hydrolase , Cyclic ADP Ribose Hydro
Gene, Accession #CD38, Gene ID: 952, UniProt: P28907
Catalog #abx010525
Priceplease inquire
Order / More InfoCyclic ADP Ribose Hydrolase (CD38) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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