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Antigenic Specificity | Cyclic ADP Ribose Hydrolase (CD38) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | ascites |
Size | 100 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD38 is a type II integral membrane glycoprotein which is present on early B and T cell lineages and activated B and T cells but is absent from most mature resting peripheral lymphocytes. CD38 is also found on thymocytes, pre-B cells, germinal center B cells, mitogen-activated T cells, monocytes and Ig-secreting plasma cells. CD38 acts as a NAD glycohydrolase in T lym- phocytes. On hematopoietic cells CD38 induces activation, proliferation, and differentiation of mature T and B cells and mediates apoptosis of myeloid and lymphoid progenitor cells. In addition to acting as a signaling receptor, CD38 is also an enzyme capable of producing several calcium-mobilizing metabo- lites, including cyclic adenosine diphosphate ribose (cADPR). CD38 also plays a role in maintaining survival of an invariant NK T (iNKT) cell subset that preferentially contributes to the maintenance of immunological tolerance. |
Immunogen | Purified recombinant fragment of human CD38 expressed in E. Coli. |
Other Names | CD38, Cyclic ADP Ribose Hydrolase, Cyclic ADP Ribose Hydrolase 1, CD38 Molecule, ADP-Ribosyl Cyclase 1, 2-Phospho-Cyclic-ADP-Ribose Transferase, Cyclic ADP-Ribose Hydrolase 1, 2-Phospho-ADP-Ribosyl Cyclase, NAD(+) Nucleosidase, CD38 Antigen (P45), ADPRC, ADPRC 1, 2-Phospho-ADP-Ribosyl Cyclase/2-Phospho-Cyclic-ADP-Ribose Transferase, 2-Phospho-ADP-Ribosyl Cyclase, 2-Phospho-Cyclic-ADP-Ribose Transferase, Ecto-Nicotinamide Adenine Dinucleotide Glycohydrolase, ADP-Ribosyl Cyclase/Cyclic ADP-Ribose Hydrolase 1, ADP-Ribosyl Cyclase, Cyclic ADP-Ribose Hydrolase 1, Cluster Of Differentiation 38, CADPr Hydrolase 1, CD38 Antigen, EC 2.4.99.20, EC 3.2.2.6, ADPRC1, T10, cADPRH, cADPRH 1, cADPRH1, 2'-phospho-ADP-ribosyl cyclase, 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase, 2'-phospho-cyclic-ADP-ribose transferase, cADPr hydrolase 1, CD38, CD38, CD38 , CD38 , Cyclic ADP Ribose Hydrolase, Cyclic ADP Ribose Hydrolase, Cyclic ADP Ribose Hydrolase , Cyclic ADP Ribose Hydro |
Gene, Accession # | CD38, Gene ID: 952, UniProt: P28907 |
Catalog # | abx010525 |
Price | please inquire |
Order / More Info | Cyclic ADP Ribose Hydrolase (CD38) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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