Edit |   |
---|---|
Antigenic Specificity | Glutamate Decarboxylase 1 (GAD1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | > 0.5 mg/ml |
Applications | WB, IHC, IF/ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Glutamate Decarboxylase 1 (GAD1) Antibody is a Rabbit Polyclonal antibody against Glutamate Decarboxylase 1 (GAD1). This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form. |
Immunogen | A synthetic peptide of human GAD1. |
Other Names | GAD1, Glutamate Decarboxylase 1, Glutamate Decarboxylase 1 (Brain, 67kDa), Glutamate Decarboxylase 67 KDa Isoform, 67 KDa Glutamic Acid Decarboxylase, GAD-67, GAD, Glutamate Decarboxylase 1 (Brain, 67kD), EC 4.1.1.15, CPSQ1, GAD67, SCP, GAD1, GAD1, GAD1, GAD1, Glutamate Decarboxylase 1, Glutamate Decarboxylase 1, Glutamate Decarboxylase 1, Glutamate Decarboxylase 1, Glutamate Decarboxylase 1 (Brain, 67kDa), Glutamate Decarboxylase 1 (Brain, 67kDa), Glutamate Decarboxylase 1 (Brain, 67kDa), Glutamate Decarboxylase 1 (Brain, 67kDa), Glutamate Decarboxylase 67 KDa Isoform, Glutamate Decarboxylase 67 KDa Isoform, Glutamate Decarboxylase 67 KDa Isoform, Glutamate Decarboxylase 67 KDa Isoform, 67 KDa Glutamic Acid Decarboxylase, 67 KDa Glutamic Acid Decarboxylase, 67 KDa Glutamic Acid Decarboxylase, 67 KDa Glutamic Acid Decarboxylase, GAD-67, GAD-67, GAD-67, GAD-67, GAD, GAD, GAD, GAD, Glutamate Decarboxylase 1 (Brain, 67kD), Glutamate Decarboxylase 1 (Brain, 67kD), Glutamate Decarboxylase 1 (Brain, 67kD), Glutamate Decarboxylase 1 (Brain, 67kD), EC 4.1.1.15, EC 4.1.1.15, EC 4.1.1.15, EC 4.1.1.15, CPSQ1, CPSQ1, CPSQ1, CPSQ1, GAD67, GAD67, GAD67, GAD67, SCP, SCP, SCP, SCP |
Gene, Accession # | GAD1, Gene ID: 2571, 14415, NCBI Accession: NP_000808.2, UniProt: Q99259, P48318, P18088 |
Catalog # | abx002144 |
Price | please inquire |
Order / More Info | Glutamate Decarboxylase 1 (GAD1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950