Edit |   |
---|---|
Antigenic Specificity | Suppressor of Variegation 3-9 Homolog 2 (SUV39H2) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | Protein G purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The murine gene Suv39h2 encodes an H3 histone methyltransferase (HMTase) 59% identical in sequence to mouse Suv39h1. During embryogenesis, both proteins overlap in tissue expression, yet Suv39h2 transcripts are restricted to the testes in adult animals. Immunolocalization of the Suv39h2 protein during spermatogenesis indicates enrichment at the heterochromatin from the leptotene to the round spermatid stage. Moreover, Suv39h2 specifically accumulates with chromatin of the sex chromosomes, which undergo transcriptional silencing during the first meiotic prophase. Suv39h2 HMTase may also organize meiotic heterochromatin with the potential for epigenetic imprint to the male germline. |
Immunogen | KLH-conjugated synthetic peptide between 360-390 amino acids from the C-terminal region of human SUV39H2. |
Other Names | FLJ23414, KMT1B, Histone H3-K9 methyltransferase 2, H3-K9-HMTase 2, Lysine N-methyltransferase 1B, Suppressor of variegation 3-9 homolog 2, Su(var)3-9 homolog 2, SUV39H2, Histone-lysine N-methyltransferase SUV39H2, Su (var)3-9 homolog 2, suppressor of variegation 3-9 homolog 2 (Drosophila), suppressor of variation 3-9 (Drosophila) homolog 2 (Drosophila), RP11-2K17.2, KMT1, uppressor of variegation 3-9 homolog 2 (Drosophila), FLJ23414, FLJ23414, FLJ23414 , FLJ23414 , KMT1B, KMT1B, KMT1B , KMT1B , Histone H3-K9 methyltransferase 2, Histone H3-K9 methyltransferase 2, Histone H3-K9 methyltransferase 2 , Histone H3-K9 methyltransferase 2 , H3-K9-HMTase 2, H3-K9-HMTase 2, H3-K9-HMTase 2 , H3-K9-HMTase 2 , Lysine N-methyltransferase 1B, Lysine N-methyltransferase 1B, Lysine N-methyltransferase 1B , Lysine N-methyltransferase 1B , Suppressor of variegation 3-9 homolog 2, Suppressor of variegation 3-9 homolog 2, Suppressor of variegation 3-9 homolog 2 , Suppressor of variegation 3-9 homol |
Gene, Accession # | NCBI: NP_001180353.1, NP_001180354.1, NP_001180355.1, NP_001180356.1, NP_078946.1, UniProt: Q9H5I1 |
Catalog # | abx027036 |
Price | please inquire |
Order / More Info | Suppressor of Variegation 3-9 Homolog 2 (SUV39H2) Antibody from ABBEXA LTD |
Product Specific References | n/a |
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950