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Antigenic Specificity | Zona Pellucida Glycoprotein 4 (ZP4) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a consensus furin cleavage site, and a C-terminal transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies. Previously, this gene has been referred to as ZP1 or ZPB and thought to have similar functions as mouse Zp1. However, a human gene with higher similarity and chromosomal synteny to mouse Zp1 has been assigned the symbol ZP1 and this gene has been assigned the symbol ZP4. |
Immunogen | KLH-conjugated synthetic peptide between 445-474 amino acids from the C-terminal region of human ZP4. |
Other Names | ZBP, zona pellucida sperm-binding 4, zona pellucida sperm-binding B, ZP1, ZPB, ZP4, Zona pellucida sperm-binding protein 4, Zona pellucida glycoprotein 4, Zona pellucida protein B, Processed zona pellucida sperm-binding protein 4, ZBP, ZBP, ZBP , ZBP , zona pellucida sperm-binding 4, zona pellucida sperm-binding 4, zona pellucida sperm-binding 4 , zona pellucida sperm-binding 4 , zona pellucida sperm-binding B, zona pellucida sperm-binding B, zona pellucida sperm-binding B , zona pellucida sperm-binding B , ZP1, ZP1, ZP1 , ZP1 , ZPB, ZPB, ZPB , ZPB , ZP4, ZP4, ZP4 , ZP4 , Zona pellucida sperm-binding protein 4, Zona pellucida sperm-binding protein 4, Zona pellucida sperm-binding protein 4 , Zona pellucida sperm-binding protein 4 , Zona pellucida glycoprotein 4, Zona pellucida glycoprotein 4, Zona pellucida glycoprotein 4 , Zona pellucida glycoprotein 4 , Zona pellucida protein B, Zona pellucida protein B, Zona pellucida protein B , Zona pellucida protein B , Processed zona pel |
Gene, Accession # | UniProt: Q12836 |
Catalog # | abx026976 |
Price | please inquire |
Order / More Info | Zona Pellucida Glycoprotein 4 (ZP4) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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