Protein Phosphatase 4 Catalytic Subunit (PPP4C) Antibody from ABBEXA LTD

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Antigenic SpecificityProtein Phosphatase 4 Catalytic Subunit (PPP4C)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size80 µl, 400 µl,
Concentrationn/a
ApplicationsELISA, WB, IHC
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DescriptionProtein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, tumor necrosis factor (TNF) alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on Ser-140 (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair. Dephosphorylates NDEL1 at CDK1 phosphorylation sites and negatively regulates CDK1 activity in interphase (By similarity).
ImmunogenKLH-conjugated synthetic peptide between 160-189 amino acids from the Central region of human PPP4C.
Other NamesPP4, PPX, PP4C, PPH3, PPP4, PPP4C, Serine/threonine-protein phosphatase 4 catalytic subunit, Protein phosphatase X, protein phosphatase 4 (formerly X), catalytic subunit, Protein phosphatase 4, catalytic subunit, protein phosphatase 4 (formerly X), catalytic subunit, PP4, PP4, PP4 , PP4 , PPX, PPX, PPX , PPX , PP4C, PP4C, PP4C , PP4C , PPH3, PPH3, PPH3 , PPH3 , PPP4, PPP4, PPP4 , PPP4 , PPP4C, PPP4C, PPP4C , PPP4C , Serine/threonine-protein phosphatase 4 catalytic subunit, Serine/threonine-protein phosphatase 4 catalytic subunit, Serine/threonine-protein phosphatase 4 catalytic subunit , Serine/threonine-protein phosphatase 4 catalytic subunit , Protein phosphatase X, Protein phosphatase X, Protein phosphatase X , Protein phosphatase X , protein phosphatase 4 (formerly X), catalytic subunit, protein phosphatase 4 (formerly X), catalytic subunit, protein phosphatase 4 (formerly X), catalytic subunit , protein phosphatase 4 (formerly X), catalytic subunit , Protein phosphatase 4
Gene, Accession #UniProt: P60510
Catalog #abx027585
Priceplease inquire
Order / More InfoProtein Phosphatase 4 Catalytic Subunit (PPP4C) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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