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Antigenic Specificity | Protein Phosphatase 4 Catalytic Subunit (PPP4C) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, tumor necrosis factor (TNF) alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on Ser-140 (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair. Dephosphorylates NDEL1 at CDK1 phosphorylation sites and negatively regulates CDK1 activity in interphase (By similarity). |
Immunogen | KLH-conjugated synthetic peptide between 160-189 amino acids from the Central region of human PPP4C. |
Other Names | PP4, PPX, PP4C, PPH3, PPP4, PPP4C, Serine/threonine-protein phosphatase 4 catalytic subunit, Protein phosphatase X, protein phosphatase 4 (formerly X), catalytic subunit, Protein phosphatase 4, catalytic subunit, protein phosphatase 4 (formerly X), catalytic subunit, PP4, PP4, PP4 , PP4 , PPX, PPX, PPX , PPX , PP4C, PP4C, PP4C , PP4C , PPH3, PPH3, PPH3 , PPH3 , PPP4, PPP4, PPP4 , PPP4 , PPP4C, PPP4C, PPP4C , PPP4C , Serine/threonine-protein phosphatase 4 catalytic subunit, Serine/threonine-protein phosphatase 4 catalytic subunit, Serine/threonine-protein phosphatase 4 catalytic subunit , Serine/threonine-protein phosphatase 4 catalytic subunit , Protein phosphatase X, Protein phosphatase X, Protein phosphatase X , Protein phosphatase X , protein phosphatase 4 (formerly X), catalytic subunit, protein phosphatase 4 (formerly X), catalytic subunit, protein phosphatase 4 (formerly X), catalytic subunit , protein phosphatase 4 (formerly X), catalytic subunit , Protein phosphatase 4 |
Gene, Accession # | UniProt: P60510 |
Catalog # | abx027585 |
Price | please inquire |
Order / More Info | Protein Phosphatase 4 Catalytic Subunit (PPP4C) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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