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Antigenic Specificity | Apoptosis Inducing Factor 1, Mitochondrial (AIFM1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | > 0.5 mg/ml |
Applications | WB, IHC, IF/ICC, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | AIFM1 antibody is a Rabbit polyclonal antibody against AIFM1. This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10. |
Immunogen | Recombinant protein of human AIFM1. |
Other Names | AIF, CMTX4, COWCK, PDCD8, COXPD6, AIFM1, Apoptosis-inducing factor 1 mitochondrial, Programmed cell death protein 8, apoptosis-inducing factor, mitochondrion-associated, 1, apoptosis-inducing factor 1, mitochondrial, programmed cell death 8, striatal apoptosis-inducing factor, Apoptosis-inducing factor 1, mitochondrial, apoptosis-inducing factor, mitochondrion-associated, 1, MGC111425, AIF, AIF, AIF , AIF , CMTX4, CMTX4, CMTX4 , CMTX4 , COWCK, COWCK, COWCK , COWCK , PDCD8, PDCD8, PDCD8 , PDCD8 , COXPD6, COXPD6, COXPD6 , COXPD6 , AIFM1, AIFM1, AIFM1 , AIFM1 , Apoptosis-inducing factor 1 mitochondrial, Apoptosis-inducing factor 1 mitochondrial, Apoptosis-inducing factor 1 mitochondrial , Apoptosis-inducing factor 1 mitochondrial , Programmed cell death protein 8, Programmed cell death protein 8, Programmed cell death protein 8 , Programmed cell death protein 8 , apoptosis-inducing factor, mitochondrion-associated, 1, apoptosis-inducing factor, mitochondrion-associated, 1, apopto |
Gene, Accession # | AIFM1, Gene ID: 9131, UniProt: O95831 |
Catalog # | abx002005 |
Price | please inquire |
Order / More Info | Apoptosis Inducing Factor 1, Mitochondrial (AIFM1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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