Apoptosis Inducing Factor 1, Mitochondrial (AIFM1) Antibody from ABBEXA LTD

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Antigenic SpecificityApoptosis Inducing Factor 1, Mitochondrial (AIFM1)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size20 µl, 50 µl, 100 µl, 200 µl
Concentration> 0.5 mg/ml
ApplicationsWB, IHC, IF/ICC, IP
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DescriptionAIFM1 antibody is a Rabbit polyclonal antibody against AIFM1. This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10.
ImmunogenRecombinant protein of human AIFM1.
Other NamesAIF, CMTX4, COWCK, PDCD8, COXPD6, AIFM1, Apoptosis-inducing factor 1 mitochondrial, Programmed cell death protein 8, apoptosis-inducing factor, mitochondrion-associated, 1, apoptosis-inducing factor 1, mitochondrial, programmed cell death 8, striatal apoptosis-inducing factor, Apoptosis-inducing factor 1, mitochondrial, apoptosis-inducing factor, mitochondrion-associated, 1, MGC111425, AIF, AIF, AIF , AIF , CMTX4, CMTX4, CMTX4 , CMTX4 , COWCK, COWCK, COWCK , COWCK , PDCD8, PDCD8, PDCD8 , PDCD8 , COXPD6, COXPD6, COXPD6 , COXPD6 , AIFM1, AIFM1, AIFM1 , AIFM1 , Apoptosis-inducing factor 1 mitochondrial, Apoptosis-inducing factor 1 mitochondrial, Apoptosis-inducing factor 1 mitochondrial , Apoptosis-inducing factor 1 mitochondrial , Programmed cell death protein 8, Programmed cell death protein 8, Programmed cell death protein 8 , Programmed cell death protein 8 , apoptosis-inducing factor, mitochondrion-associated, 1, apoptosis-inducing factor, mitochondrion-associated, 1, apopto
Gene, Accession #AIFM1, Gene ID: 9131, UniProt: O95831
Catalog #abx002005
Priceplease inquire
Order / More InfoApoptosis Inducing Factor 1, Mitochondrial (AIFM1) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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