HLA class I histocompatibility antigen, B alpha chain (HLA-B) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-HLA class I histocompatibility antigen, B alpha chain (HLA-B) antibody, protein, ELISA kits.
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| Antigenic Specificity | HLA class I histocompatibility antigen, B alpha chain (HLA-B) |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgM |
| Format | purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exon 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-B alleles have been described. |
| Immunogen | KLH-conjugated synthetic peptide between 62-90 amino acids from human HLA-B. |
| Other Names | AS, HLA-B-7301, HLA-B73, HLAB, HLAC, MGC111087, SPDA1, HLA-B, HLA class I histocompatibility antigen, B-27 alpha chain, MHC class I antigen B*27, B-7 alpha chain, MHC class I antigen B*7, MHC Class I HLA heavy chain, Leukocyte antigen class I-B, major histocompatibility complex, class I, B, HLA class I histocompatibility antigen, B alpha chain, MHC HLA-B cell surface glycoprotein, MHC HLA-B transmembrane glycoprotein, MHC class I antigen GN0010, Hla-Bhla-B Protein, AS, AS, AS , AS , HLA-B-7301, HLA-B-7301, HLA-B-7301 , HLA-B-7301 , HLA-B73, HLA-B73, HLA-B73 , HLA-B73 , HLAB, HLAB, HLAB , HLAB , HLAC, HLAC, HLAC , HLAC , MGC111087, MGC111087, MGC111087 , MGC111087 , SPDA1, SPDA1, SPDA1 , SPDA1 , HLA-B, HLA-B, HLA-B , HLA-B , HLA class I histocompatibility antigen, HLA class I histocompatibility antigen, HLA class I histocompatibility antigen , HLA class I histocompatibility antigen , B-27 alpha chain, B-27 alpha chain, B-27 alpha chain , B-27 alpha chain , MHC class I antigen |
| Gene, Accession # | UniProt: P01889 |
| Catalog # | abx025003 |
| Price | please inquire |
| Order / More Info | HLA class I histocompatibility antigen, B alpha chain (HLA-B) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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