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Antigenic Specificity | Metastasis-Suppressor KiSS-1 (KISS1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | > 0.5 mg/ml |
Applications | WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | KISS1 antibody is a Rabbit polyclonal antibody against KISS1. This gene is a metastasis suppressor gene that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity. The encoded protein may inhibit chemotaxis and invasion and thereby attenuate metastasis in malignant melanomas. Studies suggest a putative role in the regulation of events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. A protein product of this gene, kisspeptin, stimulates gonadotropin-releasing hormone (GnRH)-induced gonadotropin secretion and regulates the pubertal activation of GnRH nuerons. A polymorphism in the terminal exon of this mRNA results in two protein isoforms. An adenosine present at the polymorphic site represents the third position in a stop codon. When the adenosine is absent, a downstream stop codon is utilized and the encoded protein extends for an additional seven amino acid residues. |
Immunogen | A synthetic peptide of human KISS1. |
Other Names | KISS1, KiSS-1 Metastasis-Suppressor, Prepro-Kisspeptin, Kisspeptin-1, Malignant Melanoma Metastasis-Suppressor, Metastasis-Suppressor KiSS-1, Kisspeptin, Metastin, KiSS-1, HH13, Kisspeptin 1, KISS1, KISS1, KISS1 , KISS1 , KiSS-1 Metastasis-Suppressor, KiSS-1 Metastasis-Suppressor, KiSS-1 Metastasis-Suppressor , KiSS-1 Metastasis-Suppressor , Prepro-Kisspeptin, Prepro-Kisspeptin, Prepro-Kisspeptin , Prepro-Kisspeptin , Kisspeptin-1, Kisspeptin-1, Kisspeptin-1 , Kisspeptin-1 , Malignant Melanoma Metastasis-Suppressor, Malignant Melanoma Metastasis-Suppressor, Malignant Melanoma Metastasis-Suppressor , Malignant Melanoma Metastasis-Suppressor , Metastasis-Suppressor KiSS-1, Metastasis-Suppressor KiSS-1, Metastasis-Suppressor KiSS-1 , Metastasis-Suppressor KiSS-1 , Kisspeptin, Kisspeptin, Kisspeptin , Kisspeptin , Metastin, Metastin, Metastin , Metastin , KiSS-1, KiSS-1, KiSS-1 , KiSS-1 , HH13, HH13, HH13 , HH13 , Kisspeptin 1, Kisspeptin 1, Kisspeptin 1 , Kisspeptin 1 |
Gene, Accession # | KISS1, Gene ID: 3814, UniProt: Q15726 |
Catalog # | abx002171 |
Price | please inquire |
Order / More Info | Metastasis-Suppressor KiSS-1 (KISS1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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