Endoplasmic Reticulum-Associated Amyloid Beta-Peptide-Binding Protein (ERAB) Antibody from ABBEXA LTD
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| Antigenic Specificity | Endoplasmic Reticulum-Associated Amyloid Beta-Peptide-Binding Protein (ERAB) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 100 µg, |
| Concentration | 2 mg/ml |
| Applications | ELISA, WB, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Endoplasmic Reticulum-Associated Amyloid Beta-Peptide-Binding Protein (ERAB) antibody is a Rabbit polyclonal antibody for the detection of ERAB. Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/TRMT10C, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends. Catalyzes the beta-oxidation at position 17 of androgens and estrogens and has 3-alpha-hydroxysteroid dehydrogenase activity with androsterone. Catalyzes the third step in the beta-oxidation of fatty acids. Carries out oxidative conversions of 7-alpha-OH and 7-beta-OH bile acids. Also exhibits 20-beta-OH and 21-OH dehydrogenase activities with C21 steroids. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD). |
| Immunogen | hydroxysteroid(17-beta) dehydrogenase 10 |
| Other Names | 17 beta HSD 10, 17b HSD10, ABAD, CAMR, DUPXp11.22, ERAB, HADH2, HCD2, HSD17B10, MHBD, MRPP2, MRX17, MRX31, MRXS10, SCHAD, SDR5C1, Type II HADH, XH98G2, 17 beta HSD 10, 17 beta HSD 10, 17 beta HSD 10 , 17 beta HSD 10 , 17b HSD10, 17b HSD10, 17b HSD10 , 17b HSD10 , ABAD, ABAD, ABAD , ABAD , CAMR, CAMR, CAMR , CAMR , DUPXp11.22, DUPXp11.22, DUPXp11.22 , DUPXp11.22 , ERAB, ERAB, ERAB , ERAB , HADH2, HADH2, HADH2 , HADH2 , HCD2, HCD2, HCD2 , HCD2 , HSD17B10, HSD17B10, HSD17B10 , HSD17B10 , MHBD, MHBD, MHBD , MHBD , MRPP2, MRPP2, MRPP2 , MRPP2 , MRX17, MRX17, MRX17 , MRX17 , MRX31, MRX31, MRX31 , MRX31 , MRXS10, MRXS10, MRXS10 , MRXS10 , SCHAD, SCHAD, SCHAD , SCHAD , SDR5C1, SDR5C1, SDR5C1 , SDR5C1 , Type II HADH, Type II HADH, Type II HADH , Type II HADH , XH98G2, XH98G2, XH98G2 , XH98G2 |
| Gene, Accession # | HSD17B10, Gene ID: 3028, UniProt: Q99714 |
| Catalog # | abx020130 |
| Price | please inquire |
| Order / More Info | Endoplasmic Reticulum-Associated Amyloid Beta-Peptide-Binding Protein (ERAB) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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