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Antigenic Specificity | Low Density Lipoprotein Receptor Related Protein 6 (LRP6) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 20 µl, 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | LRP6 is essential for the Wnt/beta catenin signaling pathway, probably by acting as a coreceptor together with Frizzled for Wnt. It is a specific, high-affinity receptor for DKK1 and DKK2, but not DKK3. The interaction with DKK1 blocks LRP6-mediated Wnt/beta catenin signaling via LRP6 removal via Kremen proteins-mediated endocytosis. |
Immunogen | KLH-conjugated synthetic peptide between 1531-1560 amino acids from the C-terminal region of human LRP6. |
Other Names | ADCAD2, Low Density Lipoprotein Receptor Related Protein 6, LRP6, LRP-6, low density lipoprotein receptor-related protein 6, low density lipoprotein-related protein 6, FLJ90062, FLJ90421, Low-density lipoprotein receptor-related protein 6, ADCAD2, ADCAD2, ADCAD2 , ADCAD2 , Low Density Lipoprotein Receptor Related Protein 6, Low Density Lipoprotein Receptor Related Protein 6, Low Density Lipoprotein Receptor Related Protein 6 , Low Density Lipoprotein Receptor Related Protein 6 , LRP6, LRP6, LRP6 , LRP6 , LRP-6, LRP-6, LRP-6 , LRP-6 , low density lipoprotein receptor-related protein 6, low density lipoprotein receptor-related protein 6, low density lipoprotein receptor-related protein 6 , low density lipoprotein receptor-related protein 6 , low density lipoprotein-related protein 6, low density lipoprotein-related protein 6, low density lipoprotein-related protein 6 , low density lipoprotein-related protein 6 , FLJ90062, FLJ90062, FLJ90062 , FLJ90062 , FLJ90421, FLJ90421, FLJ904 |
Gene, Accession # | LRP6, Gene ID: 4040, NCBI: NP_002327.2, UniProt: O75581 |
Catalog # | abx032705 |
Price | please inquire |
Order / More Info | Low Density Lipoprotein Receptor Related Protein 6 (LRP6) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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