NFkB p65 Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-NFkB p65 antibody, protein, ELISA kits.
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| Antigenic Specificity | NFkB p65 |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human, mouse |
| Isotype | IgG1 |
| Format | ascites |
| Size | 100 µl, |
| Concentration | n/a |
| Applications | ELISA, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Transcription factors of the nuclear factor kappa B (NF- kappa B)/Rel family is a ubiquitously expressed transcription factor that regulates many cytokine and Ig genes. It is involved in immune, inflammatory, viral, and acute phase responses. There are five family members in mammals: RelA (p65), c-Rel, RelB, NF- kappa B1 (p105/p50) and NF- kappa B2 (p100/p52). The most studied NF- kappa B complex consists of the p50 and p65 subunits, both containing a 300 amino acid region with homology to the Rel proto-oncogene product. The p50 subunit binds DNA, whereas the p65 subunit is responsible for the interaction of NF- kappa B with its inhibitor, I kappa B. In most cell types, the p50/p65 heterodimer is located within the cytoplasm complexed to I kappa B. This complex prevents nuclear translocation and activity of NF- kappa B. In response to stimuli such as cytokines, LPS, and viral infections, I kappa B is phosphorylated at critical residues. This phosphorylation induces dissociation of the I kappa B/NF- kappa B complex, allowing the free heterodimeric NF- kappa B to form a heterotetramer that translocates to the nucleus. In the nucleus, it binds to the kappa B site within promoters and enhancers and functions as a transcriptional activator. |
| Immunogen | Purified recombinant fragment of human NF-kB p65 expressed in E. Coli. |
| Other Names | NF- kappa B p65, NF-kappaB p65, NFkappaB p65, p65, NFKB3, RELA, NFkB P65, NF kappa beta p65, nuclear factor NF-kappa-B p65 subunit, TF65, transcription factor p65, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, NF- kappa B p65, NF- kappa B p65 , NF- kappa B p65 , NF- kappa B p65, NF-kappaB p65, NF-kappaB p65 , NF-kappaB p65 , NF-kappaB p65, NFkappaB p65, NFkappaB p65 , NFkappaB p65 , NFkappaB p65, p65, p65 , p65 , p65, NFKB3, NFKB3 , NFKB3 , NFKB3, RELA, RELA , RELA , RELA, NFkB P65, NFkB P65 , NFkB P65 , NFkB P65, NF kappa beta p65, NF kappa beta p65 , NF kappa beta p65 , NF kappa beta p65, nuclear factor NF-kappa-B p65 subunit, nuclear factor NF-kappa-B p65 subunit , nuclear factor NF-kappa-B p65 subunit , nuclear factor NF-kappa-B p65 subunit, TF65, TF65 , TF65 , TF65, transcription factor p65, transcription factor p65 , transcription factor p65 , transcription factor p65, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, Nuclear |
| Gene, Accession # | Gene ID: 5970, UniProt: Q04206 |
| Catalog # | abx012273 |
| Price | please inquire |
| Order / More Info | NFkB p65 Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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