5'-Nucleotidase / CD73 (NT5E) Antibody from ABBEXA LTD

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Antigenic Specificity5'-Nucleotidase / CD73 (NT5E)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
FormatProtein G purified
Size80 µl, 400 µl,
Concentrationn/a
ApplicationsELISA, WB, IHC
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DescriptionEcto-5-prime-nucleotidase (5-prime-ribonucleotide phosphohydrolase) catalyzes the conversion at neutral pH of purine 5-prime mononucleotides to nucleosides, the preferred substrate being AMP. The enzyme consists of a dimer of 2 identical 70 kD subunits bound externally to the plasma membrane by a glycosyl phosphatidyl inositol linkage. The enzyme is used as a marker of lymphocyte differentiation. Consequently, a deficiency of NT5E occurs in a variety of immunodeficiency diseases. Other forms of 5-prime nucleotidase exist in the cytoplasm and lysosomes and can be distinguished from ecto-NT5 by their substrate affinities, requirement for divalent magnesium ion, activation by ATP, and inhibition by inorganic phosphate. It is not known whether the different enzymes are coded by different genes or result from different posttranslational modifications of a single coding sequence.
ImmunogenKLH-conjugated synthetic peptide between 520-550 amino acids from the C-terminal region of human CD73 (NT5E).
Other NamesCD73, NT5, 5' NT, 5' nucleotidase, 5' nucleotidase precursor, 5'-NT, 5'-nucleotidase, CD73 antigen, E5NT, Ecto 5' nucleotidase, Ecto-5'-nucleotidase, eN eNT, NT NT5, NT5E, NTE, Purine 5 Prime Nucleotidase, CD antigen CD73, CD73, CD73, CD73 , CD73 , NT5, NT5, NT5 , NT5 , 5' NT, 5' NT, 5' NT , 5' NT , 5' nucleotidase, 5' nucleotidase, 5' nucleotidase , 5' nucleotidase , 5' nucleotidase precursor, 5' nucleotidase precursor, 5' nucleotidase precursor , 5' nucleotidase precursor , 5'-NT, 5'-NT, 5'-NT , 5'-NT , 5'-nucleotidase, 5'-nucleotidase, 5'-nucleotidase , 5'-nucleotidase , CD73 antigen, CD73 antigen, CD73 antigen , CD73 antigen , E5NT, E5NT, E5NT , E5NT , Ecto 5' nucleotidase, Ecto 5' nucleotidase, Ecto 5' nucleotidase , Ecto 5' nucleotidase , Ecto-5'-nucleotidase, Ecto-5'-nucleotidase, Ecto-5'-nucleotidase , Ecto-5'-nucleotidase , eN eNT, eN eNT, eN eNT , eN eNT , NT NT5, NT NT5, NT NT5 , NT NT5 , NT5E, NT5E, NT5E , NT5E , NTE, NTE, NTE , NTE , Purine 5 Prime Nucleotid
Gene, Accession #NCBI: NP_001191742.1, NP_002517.1, UniProt: P21589
Catalog #abx031411
Priceplease inquire
Order / More Info5'-Nucleotidase / CD73 (NT5E) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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