STIP1 Homology And U-Box Containing Protein 1 (STUB1) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-STIP1 Homology And U-Box Containing Protein 1 (STUB1) antibody, protein, ELISA kits.
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| Antigenic Specificity | STIP1 Homology And U-Box Containing Protein 1 (STUB1) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CHIP is an E3 ligase for nNOS whose action is facilitated by (and possibly requires) its interaction with nNOS-bound hsp70. Co-chaperone CHIP, possibly with another E3 ligase (s), modulates the ubiquitylation of mutant Cu/Zn-superoxide dismutase and renders them more susceptible for proteasomal degradation. CHIP functions as a negative regulator of AR transcriptional activity by promoting AR degradation. CHIP-Hsc70 complex ubiquitinates phosphorylated tau and enhances cell survival. CHIP can interact with the Smad1/Smad4 proteins and block BMP signal transduction through the ubiquitin-mediated degradation of Smad proteins. CHIP E3 controls both the association of Hsp70/Hsp90 chaperones with ErbB2 and the down-regulation of ErbB2 induced by inhibitors of Hsp90. CHIP is associated with Parkin and enhances its ubiquitin ligase activity related to Parkinson's disease. |
| Immunogen | KLH-conjugated synthetic peptide between 203-231 amino acids from the C-terminal region of human STUB1. |
| Other Names | E3 ubiquitin-protein ligase CHIP, Antigen NY-CO-7, STUB1, CHIP, CLL-associated antigen KW-8, Carboxy terminus of Hsp70-interacting protein, STIP1 homology and U box-containing protein 1, HSPABP2, NY-CO-7, SDCCAG7, UBOX1, E3 ubiquitin-protein ligase CHIP, E3 ubiquitin-protein ligase CHIP, E3 ubiquitin-protein ligase CHIP , E3 ubiquitin-protein ligase CHIP , Antigen NY-CO-7, Antigen NY-CO-7, Antigen NY-CO-7 , Antigen NY-CO-7 , STUB1, STUB1, STUB1 , STUB1 , CHIP, CHIP, CHIP , CHIP , CLL-associated antigen KW-8, CLL-associated antigen KW-8, CLL-associated antigen KW-8 , CLL-associated antigen KW-8 , Carboxy terminus of Hsp70-interacting protein, Carboxy terminus of Hsp70-interacting protein, Carboxy terminus of Hsp70-interacting protein , Carboxy terminus of Hsp70-interacting protein , STIP1 homology and U box-containing protein 1, STIP1 homology and U box-containing protein 1, STIP1 homology and U box-containing protein 1 , STIP1 homology and U box-containing protein 1 , HSPABP2, |
| Gene, Accession # | NCBI: NP_005852.2, UniProt: Q9UNE7 |
| Catalog # | abx025112 |
| Price | please inquire |
| Order / More Info | STIP1 Homology And U-Box Containing Protein 1 (STUB1) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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