COP9 Signalosome Subunit 2 (COPS2) Antibody from ABBEXA LTD

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Antigenic SpecificityCOP9 Signalosome Subunit 2 (COPS2)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size80 µl, 400 µl,
Concentrationn/a
ApplicationsELISA, WB, IHC, IF/ICC
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionThis product is currently in development. The lead time for this product may be several months. Please contact us at info@abbexa.com for an updated lead time before purchasing this product.

This product is currently in development. The lead time for this product may be several months. Please contact us at info@abbexa.com for an updated lead time before purchasing this product.

Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Involved in early stage of neuronal differentiation via its interaction with NIF3L1.
ImmunogenKLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human COPS2.
Other NamesALIEN, COP9 constitutive photomorphogenic homolog subunit 2, COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis), COP9 signalosome complex subunit 2, CSN2, JAB1-containing signalosome subunit 2, SGN2, signalosome subunit 2, thyroid receptor, thyroid receptor interacting protein 15, thyroid receptor-interacting protein 15, TRIP15, COPS2, Alien homolog, TR-interacting protein 15, TRIP-15, ALIEN, ALIEN, ALIEN , ALIEN , COP9 constitutive photomorphogenic homolog subunit 2, COP9 constitutive photomorphogenic homolog subunit 2, COP9 constitutive photomorphogenic homolog subunit 2 , COP9 constitutive photomorphogenic homolog subunit 2 , COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis), COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis), COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis) , COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis) , COP9 signalosome complex subunit 2, COP9 signalosome complex subunit
Gene, Accession #UniProt: P61201
Catalog #abx027392
Priceplease inquire
Order / More InfoCOP9 Signalosome Subunit 2 (COPS2) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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