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Antigenic Specificity | Toll-Like Receptor 6 (TLR6) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC, FCM |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TLR6, a Type I membrane protein that belongs to the Toll-like rceptor family, participates in the innate immune response to Gram-positive bacteria and fungi. It acts via MyD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. The protein recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR2. It binds to TLR2 via their respective extracellular domains, and to MyD88 via their respective TIR domains. TLR6 is detected in monocytes, CD11c+ immature dendritic cells, plasmacytoid pre-dendritic cells and dermal microvessel endothelial cells. |
Immunogen | KLH-conjugated synthetic peptide between 393-423 amino acids from the C-terminal region of human TLR6. |
Other Names | TLR3, Toll-like receptor 3, CD283, TLR6, Toll-Like Receptor 6 (TLR6) N-terminal, N-Term, RABBIT ANTI TLR6, Toll-like receptor 6, CD286, TLR3, TLR3, TLR3 , TLR3 , Toll-like receptor 3, Toll-like receptor 3, Toll-like receptor 3 , Toll-like receptor 3 , CD283, CD283, CD283 , CD283 , TLR6, TLR6, TLR6 , TLR6 , Toll-Like Receptor 6 (TLR6) N-terminal, Toll-Like Receptor 6 (TLR6) N-terminal, Toll-Like Receptor 6 (TLR6) N-terminal , Toll-Like Receptor 6 (TLR6) N-terminal , N-Term, N-Term, N-Term , N-Term , RABBIT ANTI TLR6, RABBIT ANTI TLR6, RABBIT ANTI TLR6 , RABBIT ANTI TLR6 , Toll-like receptor 6, Toll-like receptor 6, Toll-like receptor 6 , Toll-like receptor 6 , CD286, CD286, CD286 , CD286 |
Gene, Accession # | UniProt: Q9Y2C9 |
Catalog # | abx028483 |
Price | please inquire |
Order / More Info | Toll-Like Receptor 6 (TLR6) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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