Protein Kinase C Iota Type (PRKCI) Antibody from ABBEXA LTD
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| Antigenic Specificity | Protein Kinase C Iota Type (PRKCI) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | Protein G purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | PKC iota belongs to the protein kinase C (PKC) family of serine/threonine protein kinases. The PKC family comprises at least eight members, which are differentially expressed and are involved in a wide variety of cellular processes. This protein kinase is calcium-independent and phospholipid-dependent. It is not activated by phorbolesters or diacylglycerol. This kinase can be recruited to vesicle tubular clusters (VTCs) by direct interaction with the small GTPase RAB2, where this kinase phosphorylates glyceraldehydes-3-phosphate dehydrogenase (GAPD/GAPDH) and plays a role in microtubule dynamics in the early secretory pathway. This kinase is found to be necessary for BCL-ABL-mediated resistance to drug-induced apoptosis and therefore protects leukemia cells against drug-induced apoptosis. |
| Immunogen | KLH-conjugated synthetic peptide between 176-207 amino acids from the N-terminal region of human PKC iota. |
| Other Names | PKC iota, PRKCI, DXS1179E, Protein kinase C iota type, Atypical protein kinase C-lambda/iota, nPKC-iota, PKC iota, PKC iota, PKC iota , PKC iota , PRKCI, PRKCI, PRKCI , PRKCI , DXS1179E, DXS1179E, DXS1179E , DXS1179E , Protein kinase C iota type, Protein kinase C iota type, Protein kinase C iota type , Protein kinase C iota type , Atypical protein kinase C-lambda/iota, Atypical protein kinase C-lambda/iota, Atypical protein kinase C-lambda/iota , Atypical protein kinase C-lambda/iota , nPKC-iota, nPKC-iota, nPKC-iota , nPKC-iota |
| Gene, Accession # | NCBI: NP_002731.4, UniProt: P41743 |
| Catalog # | abx033120 |
| Price | please inquire |
| Order / More Info | Protein Kinase C Iota Type (PRKCI) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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