Sequestosome 1 (SQSTM1) Antibody from ABBEXA LTD
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| Antigenic Specificity | Sequestosome 1 (SQSTM1) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | Protein G purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB, IHC, IF/ICC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | SQSTM1/p62 is an adapter protein which binds ubiquitin and may regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. This protein may play a role in titin/TTN downstream signaling in muscle cells, and may also regulate signaling cascades through ubiquitination. This protein is involved in cell differentiation, apoptosis, immune response and regulation of K (+) channels. SQSTM1/p62 also appears to play a role in macroautophagic removal of intracellular protein aggregates. Cellular depletion studies of SQSTM1/p62 have indicated a role for association with LC3 and aggregate proteins in order to facilitate normal formation of the autophagosome. |
| Immunogen | KLH-conjugated synthetic peptide between 317-346 amino acids from the C-terminal region of human SQSTM1 (p62). |
| Other Names | p60, p62, A170, OSIL, PDB3, ZIP3, p62B, Sequestosome-1, EBI3-associated protein of 60 kDa, EBIAP, Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa, Ubi, SQSTM1, ORCA, Ubiquitin-binding protein p62, p60, p60, p60 , p60 , p62, p62, p62 , p62 , A170, A170, A170 , A170 , OSIL, OSIL, OSIL , OSIL , PDB3, PDB3, PDB3 , PDB3 , ZIP3, ZIP3, ZIP3 , ZIP3 , p62B, p62B, p62B , p62B , Sequestosome-1, Sequestosome-1, Sequestosome-1 , Sequestosome-1 , EBI3-associated protein of 60 kDa, EBI3-associated protein of 60 kDa, EBI3-associated protein of 60 kDa , EBI3-associated protein of 60 kDa , EBIAP, EBIAP, EBIAP , EBIAP , Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa, Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa, Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa , Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa , Ubi, Ubi, Ubi , Ubi , SQSTM1, SQSTM1, SQSTM1 , SQSTM1 , ORCA, ORCA, ORCA , ORCA |
| Gene, Accession # | NCBI: NP_001135770.1, NP_001135771.1, NP_003891.1, UniProt: Q13501 |
| Catalog # | abx031570 |
| Price | please inquire |
| Order / More Info | Sequestosome 1 (SQSTM1) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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