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Antigenic Specificity | MEK Kinase Kinase 4 (MAP4K4) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | ascites |
Size | 100 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | MAP4K4: mitogen-activated protein kinase kinase kinase kinase 4.The protein encoded by this gene is a member of the serine/threonine protein kinase family.This kinase has been shown to specifically activate MAPK8/JNK.The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway.Alternatively spliced transcript variants encoding different isoforms have been identified. |
Immunogen | Purified recombinant fragment of MAP4K4 (aa400-500) expressed in E. coli. |
Other Names | HGK, NIK, MEKKK4, FLH21957, MAP4K4, FLJ10410, FLJ20373, FLJ90111, KIAA0687, HPK/GCK-like kinase HGK, M4K4, MAPK/ERK kinase kinase kinase 4, MEK kinase kinase 4, MEKKK 4, Nck interacting kinase, hepatocyte progenitor kinase-like/germinal center kinase-like kinase, mitogen-activated protein kinase kinase kinase kinase 4, HGK, HGK, HGK , HGK , NIK, NIK, NIK , NIK , MEKKK4, MEKKK4, MEKKK4 , MEKKK4 , FLH21957, FLH21957, FLH21957 , FLH21957 , MAP4K4, MAP4K4, MAP4K4 , MAP4K4 , FLJ10410, FLJ10410, FLJ10410 , FLJ10410 , FLJ20373, FLJ20373, FLJ20373 , FLJ20373 , FLJ90111, FLJ90111, FLJ90111 , FLJ90111 , KIAA0687, KIAA0687, KIAA0687 , KIAA0687 , HPK/GCK-like kinase HGK, HPK/GCK-like kinase HGK, HPK/GCK-like kinase HGK , HPK/GCK-like kinase HGK , M4K4, M4K4, M4K4 , M4K4 , MAPK/ERK kinase kinase kinase 4, MAPK/ERK kinase kinase kinase 4, MAPK/ERK kinase kinase kinase 4 , MAPK/ERK kinase kinase kinase 4 , MEK kinase kinase 4, MEK kinase kinase 4, MEK kinase kinase 4 , MEK kinase kinase |
Gene, Accession # | MAP4K4, Gene ID: 9448, UniProt: O95819 |
Catalog # | abx016036 |
Price | please inquire |
Order / More Info | MEK Kinase Kinase 4 (MAP4K4) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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