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Antigenic Specificity | PYD And CARD Domain Containing (PYCARD) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. |
Immunogen | KLH-conjugated synthetic peptide between 129-158 amino acids from the C-terminal region of human PYCARD. |
Other Names | PYCARD, ASC, CARD5, MGC10332, TMS, TMS-1, TMS1, Apoptosis-associated speck-like protein containing a CARD, Caspase recruitment domain-containing protein 5, PYD and CARD domain-containing protein, Target of methylation-induced silencing 1, PYD and CARD domain containing, 9130417A21Rik, TNS1, masc, PYCARD, PYCARD, PYCARD , PYCARD , ASC, ASC, ASC , ASC , CARD5, CARD5, CARD5 , CARD5 , MGC10332, MGC10332, MGC10332 , MGC10332 , TMS, TMS, TMS , TMS , TMS-1, TMS-1, TMS-1 , TMS-1 , TMS1, TMS1, TMS1 , TMS1 , Apoptosis-associated speck-like protein containing a CARD, Apoptosis-associated speck-like protein containing a CARD, Apoptosis-associated speck-like protein containing a CARD , Apoptosis-associated speck-like protein containing a CARD , Caspase recruitment domain-containing protein 5, Caspase recruitment domain-containing protein 5, Caspase recruitment domain-containing protein 5 , Caspase recruitment domain-containing protein 5 , PYD and CARD domain-containing protein, PYD and CA |
Gene, Accession # | PYCARD, UniProt: Q9ULZ3 |
Catalog # | abx027650 |
Price | please inquire |
Order / More Info | PYD And CARD Domain Containing (PYCARD) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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