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Antigenic Specificity | 26S Proteasome Regulatory Subunit 8 (PSMC5) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | > 0.5 mg/ml |
Applications | WB, IF/ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PSMC5 antibody is a Rabbit polyclonal antibody against PSMC5. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. In addition to participation in proteasome functions, this subunit may participate in transcriptional regulation since it has been shown to interact with the thyroid hormone receptor and retinoid X receptor-alpha. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]. |
Immunogen | Recombinant protein of human PSMC5. |
Other Names | 26S protease regulatory subunit 8, 26S proteasome AAA-ATPase subunit RPT6, Proteasome 26S subunit ATPase 5, Proteasome subunit p45, Thyroid hormone receptor-interacting protein 1, TRIP1, p45/SUG, PSMC5, SUG1, proteasome (prosome, macropain) 26S subunit, ATPase, 5, S8, p45, SUG-1, TBP10, 26S protease regulatory subunit 8, 26S protease regulatory subunit 8, 26S protease regulatory subunit 8 , 26S protease regulatory subunit 8 , 26S proteasome AAA-ATPase subunit RPT6, 26S proteasome AAA-ATPase subunit RPT6, 26S proteasome AAA-ATPase subunit RPT6 , 26S proteasome AAA-ATPase subunit RPT6 , Proteasome 26S subunit ATPase 5, Proteasome 26S subunit ATPase 5, Proteasome 26S subunit ATPase 5 , Proteasome 26S subunit ATPase 5 , Proteasome subunit p45, Proteasome subunit p45, Proteasome subunit p45 , Proteasome subunit p45 , Thyroid hormone receptor-interacting protein 1, Thyroid hormone receptor-interacting protein 1, Thyroid hormone receptor-interacting protein 1 , Thyroid hormone receptor-i |
Gene, Accession # | PSMC5, Gene ID: 5705, UniProt: P62195 |
Catalog # | abx001295 |
Price | please inquire |
Order / More Info | 26S Proteasome Regulatory Subunit 8 (PSMC5) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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