Exoribonuclease 1 (ERI1) Antibody from ABBEXA LTD
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| Antigenic Specificity | Exoribonuclease 1 (ERI1) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. A 2' and 3'-hydroxyl groups at the last nucleotide of the histone 3'-end is required for efficient degradation of RNA substrates. Also able to degrade the 3'-overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Requires for binding the 5'-ACCCA-3' sequence present in stem-loop structure. Able to bind other mRNAs. Required for 5.8S rRNA 3'-end processing. Also binds to 5.8s ribosomal RNA. Binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs. |
| Immunogen | KLH-conjugated synthetic peptide between 80-109 amino acids from the N-terminal region of human ERI1. |
| Other Names | 3'-5' exoribonuclease 1, 3'-5' exonuclease ERI1, Eri-1 homolog, Histone mRNA 3'-end-specific exoribonuclease, Histone mRNA 3'-exonuclease 1, Protein 3'hExo, HEXO, ERI1, 3'EXO, THEX1, 3'-5' exoribonuclease 1, 3'-5' exoribonuclease 1, 3'-5' exoribonuclease 1 , 3'-5' exoribonuclease 1 , 3'-5' exonuclease ERI1, 3'-5' exonuclease ERI1, 3'-5' exonuclease ERI1 , 3'-5' exonuclease ERI1 , Eri-1 homolog, Eri-1 homolog, Eri-1 homolog , Eri-1 homolog , Histone mRNA 3'-end-specific exoribonuclease, Histone mRNA 3'-end-specific exoribonuclease, Histone mRNA 3'-end-specific exoribonuclease , Histone mRNA 3'-end-specific exoribonuclease , Histone mRNA 3'-exonuclease 1, Histone mRNA 3'-exonuclease 1, Histone mRNA 3'-exonuclease 1 , Histone mRNA 3'-exonuclease 1 , Protein 3'hExo, Protein 3'hExo, Protein 3'hExo , Protein 3'hExo , HEXO, HEXO, HEXO , HEXO , ERI1, ERI1, ERI1 , ERI1 , 3'EXO, 3'EXO, 3'EXO , 3'EXO , THEX1, THEX1, THEX1 , THEX1 |
| Gene, Accession # | ERI1, UniProt: Q8IV48 |
| Catalog # | abx028868 |
| Price | please inquire |
| Order / More Info | Exoribonuclease 1 (ERI1) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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