Membrane Cofactor Protein (CD46) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-Membrane Cofactor Protein (CD46) antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Membrane Cofactor Protein (CD46) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. A number of viral and bacterial pathogens seem to exploit this property and directly induce an immunosuppressive phenotype in T-cells by binding to CD46. |
| Immunogen | KLH-conjugated synthetic peptide between 330-361 amino acids from the Central region of human CD46. |
| Other Names | CD46, MCP, MIC10, Membrane cofactor protein, TLX, Trophoblast leukocyte common antigen, MGC26544, TRA2.10, CD46, CD46, CD46 , CD46 , MCP, MCP, MCP , MCP , MIC10, MIC10, MIC10 , MIC10 , Membrane cofactor protein, Membrane cofactor protein, Membrane cofactor protein , Membrane cofactor protein , TLX, TLX, TLX , TLX , Trophoblast leukocyte common antigen, Trophoblast leukocyte common antigen, Trophoblast leukocyte common antigen , Trophoblast leukocyte common antigen , MGC26544, MGC26544, MGC26544 , MGC26544 , TRA2.10, TRA2.10, TRA2.10 , TRA2.10 |
| Gene, Accession # | NCBI: NP_002380.3, NP_722548.1, NP_758860.1, NP_758861.1, NP_758862.1, NP_758863.1, NP_758869.1, NP_758871.1, UniProt: P15529 |
| Catalog # | abx034950 |
| Price | please inquire |
| Order / More Info | Membrane Cofactor Protein (CD46) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
ABBEXA LTD
181 Cambridge Science Park
Cambridge, CB4 0GJ UK
P: +44 (0) 1223 755950
Customer Service: info@abbexa.com
Technical Support: support@abbexa.com
Orders: orders@abbexa.com
https://www.abbexa.com
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950
Profile of ABBEXA LTD
Return to Antibodies