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Antigenic Specificity | T-Cell Surface Glycoprotein CD8 Beta Chain (CD8B) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified. |
Immunogen | KLH-conjugated synthetic peptide between 141-167 amino acids from the C-terminal region of human CD8B1. |
Other Names | CD8B, CD8B1, T-cell surface glycoprotein CD8 beta chain, CD8B, CD8B, CD8B , CD8B , CD8B1, CD8B1, CD8B1 , CD8B1 , T-cell surface glycoprotein CD8 beta chain, T-cell surface glycoprotein CD8 beta chain, T-cell surface glycoprotein CD8 beta chain , T-cell surface glycoprotein CD8 beta chain |
Gene, Accession # | UniProt: P10966 |
Catalog # | abx026526 |
Price | please inquire |
Order / More Info | T-Cell Surface Glycoprotein CD8 Beta Chain (CD8B) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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