Epidermal Growth Factor Receptor (EGFR) Antibody from ABBEXA LTD

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Antigenic SpecificityEpidermal Growth Factor Receptor (EGFR)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpurified
Size80 µl, 400 µl,
Concentrationn/a
ApplicationsELISA, WB, IHC
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DescriptionEGFR is a transmembrane glycoprotein that is a member of a family of protein tyrosine kinases crucial in maintaining a normal balance in cell growth and development. A prototype member of the type 1 receptor tyrosine kinases, EGFR is encoded by the cellular oncogene cerbB1. EGFR has an extracellular ligand binding domain, a single transmembrane region, and cytoplasmic domain which is composed of a tyrosine kinase domain and a carboxy terminal domain. The carboxy terminal domain contains at least four tyrosine autophosphorylation sites. Increased production or activation of EGFR has been associated with poor prognosis in a variety of tumors. EGFR overexpression is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, stomach and in squamous cell carcinoma.
ImmunogenHuman EGFR his fusion protein.
Other NamesEGFR, epidermal growth factor receptor, erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian, HGNC:3236, ERBB, ERBB1, mENA, avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, epidermal growth fac, HER1, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, Epidermal growth factor receptor precursor, kinase EGFR, Receptor protein-tyrosine kinase ErbB-1, erbb 1, Receptor tyrosine protein kinase ErbB 1, PIG61, EGFR, EGFR, EGFR , EGFR , epidermal growth factor receptor, epidermal growth factor receptor, epidermal growth factor receptor , epidermal growth factor receptor , erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian, erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian, erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian , erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian , HGNC:3236, HGNC:3236, HGNC:3236 , HGNC:3236 , ERBB, ERBB, ERBB , ERBB , ERBB1, ERBB1, ERBB1 , ERBB1 , mENA, mENA, mENA ,
Gene, Accession #UniProt: P00533
Catalog #abx033543
Priceplease inquire
Order / More InfoEpidermal Growth Factor Receptor (EGFR) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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P: +44 (0) 1223 755950

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