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Antigenic Specificity | Myeloid Cell Surface Antigen CD33 (CD33) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2, 6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase (s) via their SH2 domain (s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro). |
Immunogen | KLH-conjugated synthetic peptide between 88-117 amino acids from the Central region of human CD33. |
Other Names | CD33, Siglec-3, gp67, p67, p68, p69, p70, p71, p72, p73, SIGLEC3, Myeloid cell surface antigen CD33, Sialic acid-binding Ig-like lectin 3, FLJ00391, CD antigen CD33, CD33, CD33, CD33 , CD33 , Siglec-3, Siglec-3, Siglec-3 , Siglec-3 , gp67, gp67, gp67 , gp67 , p67, p67, p67 , p67 , p68, p68, p68 , p68 , p69, p69, p69 , p69 , p70, p70, p70 , p70 , p71, p71, p71 , p71 , p72, p72, p72 , p72 , p73, p73, p73 , p73 , SIGLEC3, SIGLEC3, SIGLEC3 , SIGLEC3 , Myeloid cell surface antigen CD33, Myeloid cell surface antigen CD33, Myeloid cell surface antigen CD33 , Myeloid cell surface antigen CD33 , Sialic acid-binding Ig-like lectin 3, Sialic acid-binding Ig-like lectin 3, Sialic acid-binding Ig-like lectin 3 , Sialic acid-binding Ig-like lectin 3 , FLJ00391, FLJ00391, FLJ00391 , FLJ00391 , CD antigen CD33, CD antigen CD33, CD antigen CD33 , CD antigen CD33 |
Gene, Accession # | CD33, UniProt: P20138 |
Catalog # | abx027453 |
Price | please inquire |
Order / More Info | Myeloid Cell Surface Antigen CD33 (CD33) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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