Spleen Associated Tyrosine Kinase (SYK) Antibody from ABBEXA LTD

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Antigenic SpecificitySpleen Associated Tyrosine Kinase (SYK)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size100 µl,
Concentrationn/a
ApplicationsELISA, WB, IHC
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionSYK antibody is a Rabbit polyclonal antibody against SYK. Syk is a protein tyrosine kinase that plays an important role in intracellular signal transduction in hematopoietic cellsSyk interacts with immunoreceptor tyrosine-based activation motifs (ITAMs) located in the cytoplasmic domains of immune receptorsIt couples the activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including prolifeRation, differentiation, and phagocytosisThere is also evidence of a role for Syk in nonimmune cells, and investigators have indicated that Syk is a potential tumor suppressor in human breast carcinomasTyr323 is a negative regulatory phosphorylation site within the SH2-kinase linker region in SykPhosphorylation of Tyr323 provides a direct binding site to the TKB domain of CblTyrosine 352 of Syk is involved in the association of PLC-?1Tyrosines 525 and 526 are located in the activation loop of the Syk kinase domain, and phosphorylation of Tyr525/526 of human Syk (equivalent to the Tyr519/520 of mouse Syk) is essential for Syk function.
ImmunogenRecombinant protein of human SYK.
Other NamesDKFZp313N1010, FLJ25043, FLJ37489, KSYK, SYK, Spleen tyrosine kinase, kinase Syk, SYK (Ab-352), Tyrosine-protein kinase SYK, p72-Syk, DKFZp313N1010, DKFZp313N1010, DKFZp313N1010 , DKFZp313N1010 , FLJ25043, FLJ25043, FLJ25043 , FLJ25043 , FLJ37489, FLJ37489, FLJ37489 , FLJ37489 , KSYK, KSYK, KSYK , KSYK , SYK, SYK, SYK , SYK , Spleen tyrosine kinase, Spleen tyrosine kinase, Spleen tyrosine kinase , Spleen tyrosine kinase , kinase Syk, kinase Syk, kinase Syk , kinase Syk , SYK (Ab-352), SYK (Ab-352), SYK (Ab-352) , SYK (Ab-352) , Tyrosine-protein kinase SYK, Tyrosine-protein kinase SYK, Tyrosine-protein kinase SYK , Tyrosine-protein kinase SYK , p72-Syk, p72-Syk, p72-Syk , p72-Syk
Gene, Accession #SYK, Gene ID: 6850, UniProt: P43405
Catalog #abx117214
Priceplease inquire
Order / More InfoSpleen Associated Tyrosine Kinase (SYK) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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