Histone Deacetylase 1 (HDAC1) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-Histone Deacetylase 1 (HDAC1) antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Histone Deacetylase 1 (HDAC1) |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgM kappa |
| Format | purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Deacetylates SP proteins, SP1 and SP3, and regulates their function. Component of the BRG1-RB1-HDAC1 complex, which negatively regulates the CREST-mediated transcription in resting neurons. Upon calcium stimulation, HDAC1 is released from the complex and CREBBP is recruited, which facilitates transcriptional activation. Deacetylates TSHZ3 and regulates its transcriptional repressor activity. Deacetylates 'Lys-310' in RELA and thereby inhibits the transcriptional activity of NF-kappa-B. Component a RCOR/GFI/KDM1A/HDAC complex that suppresses, via histone deacetylase (HDAC) recruitment, a number of genes implicated in multilineage blood cell development. |
| Immunogen | Purified His-tagged HDAC1 protein |
| Other Names | DKFZp686H12203, GON-10, HD1, HDAC1, Histone deacetylase 1, reduced potassium dependency, yeast homolog-like 1, RPD3, RPD3L1, DKFZp686H12203, DKFZp686H12203, DKFZp686H12203 , DKFZp686H12203 , GON-10, GON-10, GON-10 , GON-10 , HD1, HD1, HD1 , HD1 , HDAC1, HDAC1, HDAC1 , HDAC1 , Histone deacetylase 1, Histone deacetylase 1, Histone deacetylase 1 , Histone deacetylase 1 , reduced potassium dependency, reduced potassium dependency, reduced potassium dependency , reduced potassium dependency , yeast homolog-like 1, yeast homolog-like 1, yeast homolog-like 1 , yeast homolog-like 1 , RPD3, RPD3, RPD3 , RPD3 , RPD3L1, RPD3L1, RPD3L1 , RPD3L1 |
| Gene, Accession # | NCBI: NP_004955.2, UniProt: Q13547 |
| Catalog # | abx034835 |
| Price | please inquire |
| Order / More Info | Histone Deacetylase 1 (HDAC1) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
ABBEXA LTD
181 Cambridge Science Park
Cambridge, CB4 0GJ UK
P: +44 (0) 1223 755950
Customer Service: info@abbexa.com
Technical Support: support@abbexa.com
Orders: orders@abbexa.com
https://www.abbexa.com
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950
Profile of ABBEXA LTD
Return to Antibodies