Dual Specificity Phosphatase 1 (DUSP1) Antibody from ABBEXA LTD

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Antigenic SpecificityDual Specificity Phosphatase 1 (DUSP1)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size20 µl, 50 µl, 100 µl, 200 µl
Concentration> 0.5 mg/ml
ApplicationsWB, IF/ICC
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DescriptionDUSP1 Antibody is a Rabbit Polyclonal antibody against DUSP1. The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus. The bacterially expressed and purified DUSP1 protein has intrinsic phosphatase activity, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues. Furthermore, it suppresses the activation of MAP kinase by oncogenic ras in extracts of Xenopus oocytes. Thus, DUSP1 may play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation.
ImmunogenA synthetic peptide of human DUSP1.
Other NamesDUSP1, dual specificity phosphatase 1, HVH1, CL100, MKP-1, PTPN10, serine/threonine specific protein phosphatase, MKP1, DUSP1, DUSP1, DUSP1, DUSP1, dual specificity phosphatase 1, dual specificity phosphatase 1, dual specificity phosphatase 1, dual specificity phosphatase 1, HVH1, HVH1, HVH1, HVH1, CL100, CL100, CL100, CL100, MKP-1, MKP-1, MKP-1, MKP-1, PTPN10, PTPN10, PTPN10, PTPN10, serine/threonine specific protein phosphatase, serine/threonine specific protein phosphatase, serine/threonine specific protein phosphatase, serine/threonine specific protein phosphatase, MKP1, MKP1, MKP1, MKP1
Gene, Accession #DUSP1, Gene ID: 1843, UniProt: P28562
Catalog #abx002140
Priceplease inquire
Order / More InfoDual Specificity Phosphatase 1 (DUSP1) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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