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Antigenic Specificity | Tyrosine-Protein Kinase ZAP-70 (ZAP70) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | ascites |
Size | 100 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. This antibody is supplied as crude ascites. |
Immunogen | Purified His-tagged Human ZAP70 protein (Fragment) |
Other Names | ZAP70, zeta-chain (TCR) associated protein kinase 70kDa, FLJ17670, FLJ17679, SRK, STD, TZK, ZAP-70, 70 kDa zeta-associated protein, syk-related tyrosine kinase, tyrosine-protein kinase ZAP-70, zeta-chain associated protein kinase, 70kD, ZA70, kinase ZAP70, ZAP70, ZAP70, ZAP70 , ZAP70 , zeta-chain (TCR) associated protein kinase 70kDa, zeta-chain (TCR) associated protein kinase 70kDa, zeta-chain (TCR) associated protein kinase 70kDa , zeta-chain (TCR) associated protein kinase 70kDa , FLJ17670, FLJ17670, FLJ17670 , FLJ17670 , FLJ17679, FLJ17679, FLJ17679 , FLJ17679 , SRK, SRK, SRK , SRK , STD, STD, STD , STD , TZK, TZK, TZK , TZK , ZAP-70, ZAP-70, ZAP-70 , ZAP-70 , 70 kDa zeta-associated protein, 70 kDa zeta-associated protein, 70 kDa zeta-associated protein , 70 kDa zeta-associated protein , syk-related tyrosine kinase, syk-related tyrosine kinase, syk-related tyrosine kinase , syk-related tyrosine kinase , tyrosine-protein kinase ZAP-70, tyrosine-protein kinase ZAP-70, tyro |
Gene, Accession # | UniProt: P43403 |
Catalog # | abx025459 |
Price | please inquire |
Order / More Info | Tyrosine-Protein Kinase ZAP-70 (ZAP70) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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