Edit |   |
---|---|
Antigenic Specificity | Germinal Center Kinase |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | Protein G purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1. |
Immunogen | KLH-conjugated synthetic peptide between 288-319 amino acids from the Central region of human Germinal Center Kinase (GCK/MAP4K2). |
Other Names | MAP4K2, GCK, RAB8IP, Mitogen-activated protein kinase kinase kinase kinase 2, B lymphocyte serine/threonine-protein kinase, Germinal center kinase, MAPK/ERK kinase kinase kinase 2, Rab8-interacting protein, MAP4K2, MAP4K2, MAP4K2 , MAP4K2 , GCK, GCK, GCK , GCK , RAB8IP, RAB8IP, RAB8IP , RAB8IP , Mitogen-activated protein kinase kinase kinase kinase 2, Mitogen-activated protein kinase kinase kinase kinase 2, Mitogen-activated protein kinase kinase kinase kinase 2 , Mitogen-activated protein kinase kinase kinase kinase 2 , B lymphocyte serine/threonine-protein kinase, B lymphocyte serine/threonine-protein kinase, B lymphocyte serine/threonine-protein kinase , B lymphocyte serine/threonine-protein kinase , Germinal center kinase, Germinal center kinase, Germinal center kinase , Germinal center kinase , MAPK/ERK kinase kinase kinase 2, MAPK/ERK kinase kinase kinase 2, MAPK/ERK kinase kinase kinase 2 , MAPK/ERK kinase kinase kinase 2 , Rab8-interacting protein, Rab8-interacting prot |
Gene, Accession # | UniProt: Q12851 |
Catalog # | abx033152 |
Price | please inquire |
Order / More Info | Germinal Center Kinase Antibody from ABBEXA LTD |
Product Specific References | n/a |
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950